19 citations
,
June 2019 in “Clinical Drug Investigation” Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
15 citations
,
July 2008 in “Journal of Dermatological Science” Ephrin-A3 helps increase and speed up hair growth in baby mice.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
14 citations
,
January 2017 in “Pharmacological Reports” TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
12 citations
,
December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Platelet-rich plasma and microneedling could potentially help hair growth in people with alopecia areata, but more research is needed.
6 citations
,
February 2012 in “American Journal of Animal and Veterinary Sciences” Growth factors are crucial for hair follicle growth and development.
5 citations
,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
1 citations
,
November 2017 in “Journal of Investigative Dermatology” Platelet-rich plasma and microneedling could potentially help hair regrowth in alopecia areata patients, but more research is needed.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
10 citations
,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
59 citations
,
September 2008 in “Experimental dermatology” Both mouse and rat models are effective for testing alopecia areata treatments.
48 citations
,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
9 citations
,
February 2022 in “Nature communications” Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
4 citations
,
December 2022 in “Frontiers in cell and developmental biology” Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” A new microneedle patch significantly improves melanoma treatment by using a special material to activate cancer-fighting drugs and disrupt cancer cells.
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene therapy in mice increased lifespan and improved health without causing cancer.
61 citations
,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
1 citations
,
October 2015 in “CRC Press eBooks” Nutricosmetics with active ingredients can help with hair loss and improve hair growth.
102 citations
,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
61 citations
,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
165 citations
,
October 2013 in “Nature Communications” Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.
51 citations
,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
37 citations
,
April 2010 in “FEBS Letters” The study concludes that the EDA2R gene is activated by p53 during chemotherapy but is not necessary for chemotherapy-induced hair loss.
28 citations
,
January 2000 in “Medical Mycology” Fungal infections in lab animals can interfere with research.
19 citations
,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
19 citations
,
March 2003 in “Journal of Investigative Dermatology” Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
14 citations
,
April 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.