5 citations
,
October 1988 in “Clinics in Dermatology” A method was developed to grow hair follicles in a lab for research on hair growth and health.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
11 citations
,
November 2011 in “The Journal of Dermatology” Connexin-26 gene mutations may increase cancer risk in KID syndrome patients.
1 citations
,
October 2007 in “The Cancer Handbook” Malignant melanoma is the deadliest skin cancer, while BCC is the most common but rarely spreads, and SCC is more aggressive than BCC.
January 2023 in “Open Life Sciences” VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.
Researchers developed a cost-effective, ethical skin model using hairless guinea pig cells for toxicology studies.
5 citations
,
September 2022 in “Antioxidants” A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
15 citations
,
December 2015 in “PLoS ONE” Fibroblasts can be mistaken for neural cells, so functional validation is needed.
9 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Metabolic processes and key genes like FGF5, FGFR1, and RRAS significantly affect hair follicle growth in Inner Mongolian Cashmere goats.
1 citations
,
July 2025 in “JCI Insight” Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
52 citations
,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
1 citations
,
November 2023 in “Journal of Microbiology and Biotechnology” Immortalized human dermal papilla cells were created that grow better and can still help form hair.
5 citations
,
March 2022 in “STAR Protocols” The method helps study hair follicle stem cells and calcium signals in mouse skin.
April 2018 in “Journal of Investigative Dermatology” Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
50 citations
,
November 2010 in “Tissue Engineering Part A” Hair follicle cells and intestinal tissue can create strong, functional blood vessel replacements.
April 2017 in “Journal of dermatological science” Researchers created a cell model to study hair growth and test hair-growth drugs.
101 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
411 citations
,
April 2010 in “Gastroenterology” Targeting colon cancer stem cells might lead to better treatment results.
25 citations
,
August 1991 in “Journal of Investigative Dermatology”
9 citations
,
January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
September 2024 in “Journal of the American Academy of Dermatology” Oxytocin receptors are found in skin cells near touch and pain neurons.
3 citations
,
January 2015 in “Sen i Gakkaishi” The new keratin film without KAPs stains better and could help study keratin functions.
36 citations
,
January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
15 citations
,
November 2020 in “Development” Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.
June 2023 in “British Journal of Dermatology” Coinheritance of BRCA2 and CYLD genes may lead to new treatment options for certain cancers.
151 citations
,
February 2006 in “Stem Cells and Development” Hair follicles can be a good source of stem cells like those from bone marrow.
21 citations
,
December 1994 in “Journal of Investigative Dermatology”