November 2021 in “Research Square (Research Square)” 3D spheroid cultures of human hair follicle cells are better for hair growth research than 2D cultures, and they provide new insights into how hair growth treatments like minoxidil and TCQA work.
January 2024 in “SSRN Electronic Journal” December 2025 in “Revista em Agronegócio e Meio Ambiente” Enriched sunflower seed oil with green coffee beans has higher antioxidants and potential for wound treatment.
94 citations
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May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
76 citations
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February 2015 in “Industrial Crops and Products” Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
67 citations
,
November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
61 citations
,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
61 citations
,
May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
47 citations
,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
46 citations
,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
42 citations
,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
40 citations
,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
29 citations
,
December 2011 in “British Journal of Dermatology” A new hair treatment with caffeine and other ingredients makes hair thicker and less likely to break.
25 citations
,
July 2017 in “Archives of Dermatological Research” Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
24 citations
,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
21 citations
,
November 2012 in “Plastic and Reconstructive Surgery” Both genetic and lifestyle factors significantly affect female hair loss.
14 citations
,
October 2020 in “Natural Products and Bioprospecting” Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
12 citations
,
May 2013 in “International Journal of Dermatology” Ethosomes improve black tea extract absorption in hair dye.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
10 citations
,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
9 citations
,
July 2014 in “PubMed” The review doesn't clearly say if biotin, caffeine, melatonin, a marine extract, and zinc are effective for treating hair loss.
8 citations
,
June 2022 in “Cosmetics” Coffee berry extract may help slow skin aging and prevent hair loss.
7 citations
,
February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
6 citations
,
August 2021 in “International Journal of Cosmetic Science” Using antioxidants on the scalp can make it healthier and decrease hair loss.
6 citations
,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
5 citations
,
January 2025 in “Pharmaceuticals” Coffea arabica shows promise for skin care due to its beneficial compounds.
5 citations
,
September 2023 in “International Journal of Molecular Sciences” FucoPol hydrogel membranes are promising for delivering drugs on the skin.
5 citations
,
August 1925 in “Archives of dermatology” An 8-year-old boy with Recklinghausen's Disease shows various symptoms and is from a family with close genetic ties.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
3 citations
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April 2019 in “Journal of Dermatological Treatment” Caffeine shows promise for treating some types of hair loss, but more research is needed.