research Can mesoporous nanoparticles promote bioavailability of topical pharmaceutics?
Smaller mesoporous nanoparticles can improve the effectiveness of topical drugs by penetrating skin furrows.
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480-510 / 1000+ resultsresearch The impact of skin massage frequency on the intrafollicular transport of silica nanoparticles: Validation of the ratchet effect on an ex vivo porcine skin model
Low-frequency skin massage helps nanoparticles penetrate hair follicles better.
research Penetration profile and human cadaver skin distribution of finasteride from vesicular nanocarriers
Ethosomal carriers effectively deliver hair loss drug into skin.
research Evaluation of the Hairless Rat as a Model for in Vivo Percutaneous Absorption
Hairless rats absorb substances through their skin more easily than hairy rats.
research In-vitro permeation of drugs into porcine hair follicles: is it quantitatively equivalent to permeation into human hair follicles?
Porcine hair follicles can effectively model human hair follicles for drug absorption.
research Cutaneous Permeation and Penetration of Sunscreens: Formulation Strategies and In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury
Erythrocyte-anchored nanoparticles improved Cepharanthine delivery and effectiveness for treating acute lung injury.
research Comparison of two encapsulated curcumin particular systems contained in different formulations with regard toin vitroskin penetration
The w/o lotion with blended cellulose improved curcumin skin penetration best.
research Skin permeation of different steroid hormones from polymeric coated liposomal formulations
Polymers increased skin permeation and stability of steroid hormones in liposomal formulations.
research On Pathways for Small Molecules Into and Out of Human Hair Fibers
Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
research Use of the skin sandwich technique to probe the role of the hair follicles in sonophoresis
Ultrasound increases skin permeability but blocks hair follicles.
research Mapping penetration of cosmetic compounds into hair fibers using time‐of‐flight secondary ion mass spectrometry (TOF‐SIMS)
Different oils penetrate hair differently; monounsaturated oils like olive oil penetrate better than polyunsaturated oils.
research In Vitro, Ex Vivo, Penetration (EpiDermTM) and in Vivo Dermatokinetics of Ketoconazole Loaded Solid Lipid Nanoparticles for Topical Delivery
Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
research Melanogenesis‐promoting effect of Cirsium japonicum flower extract in vitro and ex vivo
Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.
research Enhanced Iontophoretic Delivery of Magnesium Ascorbyl 2-Phosphate and Sodium Fluorescein to Hairless and Hairy Mouse Skin
Iontophoresis greatly improves skin absorption of certain substances, especially in hairy mice.
research Rapid high-performance liquid chromatogaphic method for detection of interindividual differences in carcinogen metabolism
Human hair follicles can assess carcinogen metabolism and imidazole compounds might be effective anticarcinogens.
research Cutaneous Drug Delivery: An Update
New methods like nanoparticles and microneedles show promise for better skin drug delivery, especially for hair disorders.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Size-dependent penetration of nanoemulsions into epidermis and hair follicles: implications for transdermal delivery and immunization
Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.
research In Vitro and In Vivo Scalp Retention and Penetration of 99mTc-Minoxidil Solution
Thicker minoxidil solutions work better and need less frequent application.
research Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery
research Electroosmotic pore transport in human skin.
research Optimization and Characterization of Cuscuta reflexa Extract Loaded Phytosomes by the Box-Behnken Design to Improve the Oral Bioavailability
Phytosomal nanocarriers can significantly increase the bioavailability of Cuscuta reflexa extract.
research Comparison of the skin penetration of Garcinia mangostana extract in particulate and non-particulate form
Encapsulated Garcinia mangostana extract in cream penetrates skin better than other forms.
research Epinephrine Vasoconstriction Effect Time in the Scalp Differs According to Injection Site and Concentration
Higher epinephrine concentration and specific injection sites increase scalp vasoconstriction time.
research A Simple Decision Tree Suited for Identification of Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation
The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.
research Skin deposition and permeation of finasteridein vitro: effects of propylene glycol, ethanol and sodium lauryl sulfate
Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
research Prevention of Follicular Penetration: Barrier-Enhancing Formulations against the Penetration of Pollen Allergens into Hair Follicles
Special creams can significantly reduce pollen allergens getting into hair follicles.
research Triggering of drug release of particles in hair follicles
New method uses hair follicles to deliver drugs deep into the skin.
research Incorporation of Isotopically Labeled Cocaine and Metabolites into Human Hair: 1. Dose-Response Relationships
Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.