April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The serum helps make hair thicker, stronger, and healthier.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The serum promotes thicker, stronger, and healthier hair.
April 2023 in “Journal of Investigative Dermatology” Cinchona succirubra extract with caffeine improves hair growth and reduces hair loss.
January 2021 in “AIP conference proceedings” A hair serum made from coffee by-products can promote hair growth and is safe, but needs less stickiness.
35 citations
,
June 2017 in “Pharmaceutical research” Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.
May 2025 in “Journal of Cosmetic Dermatology” Cuticapil Stem Hair Serum improves hair growth and reduces shedding when added to minoxidil.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
67 citations
,
November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
September 2025 in “medRxiv (Cold Spring Harbor Laboratory)” Using Centella asiatica EV and growth factors improves scalp health and hair growth.
Cinchona succirubra extract with caffeine reduces hair loss and strengthens hair.
MTS and caffeine ampoule improve hair and scalp conditions in women with hairline alopecia.
December 2024 in “Skin Appendage Disorders” Non-prescription products can help manage androgenic alopecia.
December 2020 in “Han-guk byuti gyeong-yeong hakoeji” Healthy lifestyle and weight control improve skin and scalp health in young adults.
Healthy lifestyle and weight control improve skin and scalp health in people in their 20s and 30s.
31 citations
,
February 2019 in “International Journal of Cosmetic Science” Caffeine applied to the scalp can protect hair follicles from UV damage.
8 citations
,
January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
182 citations
,
December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
12 citations
,
December 2023 in “Journal of Applied Pharmaceutical Sciences and Research” Caffeine boosts alertness, helps breathing, acts as a diuretic, and may aid cancer treatment.
4 citations
,
November 2023 in “Biological and Pharmaceutical Bulletin” The serum reduced thigh fat and improved skin firmness.
January 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” Hair growth serums reduce hair fall and improve growth with mostly positive reviews.
35 citations
,
January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
15 citations
,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
7 citations
,
October 2024 in “AAPS PharmSciTech” CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
10 citations
,
August 2014 in “Skin research and technology” Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.
2 citations
,
April 2021 in “International Journal of Pharmaceutics” Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
January 2025 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Oral minoxidil boosts hair growth and reduces shedding in androgenetic alopecia.
May 2025 in “International Journal of Cosmetic Science” Caffeine and adenosine in shampoo may boost hair growth and change scalp microbes and lipids.
46 citations
,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
17 citations
,
October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.