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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Doctors need to be better prepared to assess and treat obesity in patients.

Targeting abnormal lung fluid metabolism could reduce COVID-19 deaths and ventilator use.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Hair loss in older men is linked to higher rates of diabetes and high blood pressure.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

A blood pressure drug, diltiazem, may also help treat influenza.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

High doses of finasteride cause cell growth and tumors in mice.

Women with high androgen levels may have more severe COVID-19 symptoms.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Minoxidil in breast milk may harm nursing infants.

Recognizing and treating skin symptoms in essential thrombocythemia is crucial for patient quality of life.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.