232 citations
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October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
161 citations
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August 2013 in “Journal of experimental botany” Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.
125 citations
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May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
118 citations
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April 1998 in “Dermatologic Clinics” Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
112 citations
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January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
108 citations
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December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.
108 citations
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July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
88 citations
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February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
84 citations
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April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
83 citations
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May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
83 citations
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June 2020 in “Materials & Design” Sponge helps heal wounds faster with less inflammation and better skin/hair growth.
77 citations
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July 2020 in “European Journal of Clinical Pharmacology” Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
75 citations
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May 2013 in “Journal of the American Academy of Dermatology” Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.
58 citations
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January 2020 in “International Journal of Molecular Sciences” Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.
52 citations
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May 2017 in “Journal of Cosmetic Dermatology” PRP injections improve hair density and thickness in women with hair loss.
51 citations
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April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
45 citations
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March 2020 in “ACS Applied Materials & Interfaces” The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.
37 citations
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March 2006 in “Regulatory Peptides” Mice skin has components that could help with hair growth and might be used for diabetes treatment.
34 citations
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July 2009 in “Journal of Cell Science” ΔNp63α helps control a protein that stops cancer cells from spreading.
31 citations
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January 2007 in “Journal of biological chemistry/The Journal of biological chemistry” Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.
31 citations
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October 2010 in “Progress in lipid research” LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
29 citations
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May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
28 citations
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September 2008 in “Current Pharmaceutical Design” Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.
28 citations
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August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
27 citations
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April 2017 in “British Journal of Dermatology” Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
27 citations
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May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
26 citations
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December 2020 in “Cleveland Clinic Journal of Medicine” Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
26 citations
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May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
26 citations
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January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
25 citations
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December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.