research Modulating mechanosensory afferent excitability by an atypical mG luR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
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240-270 / 1000+ resultsresearch Modulating mechanosensory afferent excitability by an atypical
research Nociceptive and Nonnociceptive Roles of TRPV3 and Its “Druggability”
TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
research Dovobet ointment under occlusion overnight for troublesome scalp psoriasis
Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
research Penetration Enhancement of Topical Formulations
New methods improve how well skin treatments work by helping drugs get through the skin barrier.
research 344 Topical carbamide peroxide for treatment of mild to moderate acne vulgaris
10% carbamide peroxide is safe and effectively reduces mild to moderate acne.
research 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro
An oil-in-water emulsion with CBD and ginger root extract significantly improved symptoms of dry and eczema-prone skin.
research Flexible Triboelectric Nanogenerator Patch for Accelerated Wound Healing Through the Synergy of Electrostimulation and Photothermal Effect
The patch speeds up wound healing by using electricity and heat.
research Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration
The microneedle patch boosts hair growth by reducing DHT and oxidative stress.
research Temperature‐sensitive hydrogel releasing pectolinarin facilitate scarless wound healing
A hydrogel releasing pectolinarin speeds up wound healing and reduces scarring.
research Diclofenac/imiquimod
Some elderly men had healing problems after using imiquimod and diclofenac for skin conditions on their scalps.
research 898 Homeostatic activation of epidermal HSD11b1 affects skin innervation and non-histaminergic itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research The effect of Cotinus coggygria L. ethanol extract in the treatment of burn wounds
Cotinus coggygria extract cream may help heal burn wounds.
research Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol
research Effect of K+ channel openers on K+ channel in cultured human dermal papilla cells.
Increased K+ permeability alone may not promote hair growth.
research Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification
Targeting TRP channels may help reduce excessive scarring.
research 272 Structural changes in human skin after topical application of glucocorticoids assessed by in vivo imaging technologies
Topical glucocorticoids thin the skin and change collagen structure.
research A cosmetic formulation improves facial erythema in vivo
A new cosmetic cream reduced facial redness and skin temperature after 4 weeks of use.
research Effect of minoxidil sulfate and pinacidil on single potassium channel current in cultured human outer root sheath cells and dermal papilla cells
Minoxidil sulfate and pinacidil may promote hair growth through increased blood flow, not by activating potassium channels.
research A double-blind, placebo-controlled study with Kevis lotion
research Evaluating the efficacy of local anesthetic techniques during scalp microneedling
Cold gel compresses are the best for pain relief during scalp microneedling.
research TOPICAL IMMUNOTHERAPY IN DERMATOLOGY
Diphencyprone (DCP) is an effective treatment for severe alopecia areata and resistant warts, with some risks.
research TRPV3 as a Therapeutic Target for Itch
Blocking TRPV3 may help treat itch in dry skin conditions.
research The therapeutic use of topical contact sensitizers in benign dermatoses
Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.
research Ketoconazole-p Aminobenzoic Cocrystal Exhibits a Potent Anti-inflammatory Effect on the Skin of BALBc Mice
The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.
research The effect of a dietary supplement containing nicotinamide (Cavalesse®), on the severity of the symptoms in horses suffering insect bite hypersensitivity.
The nicotinamide supplement did not reduce symptoms in horses with insect bite hypersensitivity.
research The Comparative Potency of Hydrocortisone Analogs in Suppressing Growth of Hair in the Rat121From the Departments of Dermatology and Syphilology and of Anatomy, University of Michigan Medical School, Ann Arbor, Michigan.2Supported in part by research grants from the National Institutes of Health, United States Public Health Service (A-131 (C5)), the University of Michigan Memorial-Phoenix Project #145 and The Upjohn Company.
research An ROS‐Scavenging Treg‐Recruiting Hydrogel Patch for Diabetic Wound Healing
The hydrogel patch helps heal diabetic wounds by releasing a healing agent in response to harmful molecules and improving skin regeneration.
research The Pathological Culprit of Neuropathic Skin Pain in Long COVID-19 Patients: A Case Series
Long COVID-19 patients with skin pain might have a nerve condition that responds to a medication called gabapentin.
research Nanocarriers for optimizing the balance between interfollicular permeation and follicular uptake of topically applied clobetasol to minimize adverse effects
Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
research Abstract P5-11-11: A phase I safety study of topical calcitriol (BPM31543) for the prevention of chemotherapy-induced alopecia (CIA)
Topical calcitriol appears safe and may reduce hair loss during chemotherapy.