research Comparative ubiquitinomics of human skin reveals insulin receptor ubiquitination as a regulator of collagen secretion
Ubiquitination of the insulin receptor regulates collagen secretion in human skin.
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690-720 / 1000+ results research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins
Sheet formation is key to macrofibril structure differences in wool.
research A Correlative Fluorescent and Electron Microscopic Technique for Ultralocalization of Trichocyte Keratins
Researchers developed a new method to clearly see and label hair proteins with minimal errors using advanced freezing and microscopy techniques.
research Proteome Analysis of Human Hair Shaft
Human hair contains many proteins, with some being highly abundant and modified.
research Hair-Specific Keratins: Characterization and Expression of a Mouse Type I Keratin Gene
research Manganese-Doped Calcium Silicate Nanowire Composite Hydrogels for Melanoma Treatment and Wound Healing
MCSA hydrogels can effectively treat melanoma and aid wound healing.
research A discrete transition zone between cuticle and cortex layers of a human hair fibre: changes observed in the presence of breast cancer
Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Structural and Immunocytochemical Characterization of Keratinization in Vertebrate Epidermis and Epidermal Derivatives
Vertebrate skin evolved to be more specialized and complex, especially in land animals.
research The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves
Keratin from human hair helps nerves heal faster.
research ToF‐SIMS characterization of the lipid layer on the hair surface. II : Effect of the 18‐MEA lipid layer on surface hydrophobicity
18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.
research Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.
Keratinocyte growth factor significantly alters skin and tissue development.
research Soluble and insoluble collagen and elastin in the rat hair cycle
research Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Recovery and protection of photo‐damaged hairs with keratin‐encapsulated cationic liposomes
Keratin-encapsulated liposomes effectively repair and protect UV-damaged hair.
research Effect of discarded keratin-based biocomposite hydrogels on the wound healing process in vivo
Keratin-based hydrogels from human hair improve wound healing effectively.
research Platelet-rich plasma-loaded bioactive chitosan@sodium alginate@gelatin shell-core fibrous hydrogels with enhanced sustained release of growth factors for diabetic foot ulcer healing
research Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.
Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.
research Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development
research Novel Collagen Sponge Reinforced with Polyglycolic Acid Fiber Produces Robust, Normal Hair in Murine Hair Reconstitution Model
PGA fiber-reinforced collagen sponges improve hair growth and skin structure.
research Keratin expression in the human hair follicle
research Keratosis follicularis spinulosa decalvans: a family study of seven male cases and six female carriers.
The study found that males with KFSD had severe skin and eye symptoms, while female carriers had milder symptoms.
research Effect of keratin‐gelatin and bFGF‐gelatin composite film as a sandwich layer for full‐thickness skin mesh graft in experimental dogs
Keratin-gelatin films improve skin graft success in dogs.
research Structural change of keratin protein in human hair by permanent waving treatment
Permanent waving damages hair by disrupting its keratin structure.
research P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Bioinspired peptides designed for hair perming and dyeing with potential for repair
PepACS offers a safer, eco-friendly way to perm, dye, and repair hair.
research Hollow polydopamine nanoparticles loading with peptide RL-QN15: a new pro-regenerative therapeutic agent for skin wounds
HPDAlR nanoparticles greatly improve skin wound healing without toxicity.
research Mice Expressing a Mutant Krt75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita
research Keratosis Follicularis Spinulosa Decalvans: Diagnosis and Therapeutic Evaluation.
KFSD causes scarring hair loss and skin roughness, mainly in males.
research Injectable tissue adhesive composite hydrogel with fibroblasts for treating skin defects
The hydrogel helps heal skin injuries by promoting blood vessel and hair growth.