April 2023 in “Journal of Investigative Dermatology” The mTOR signaling pathway might play a role in radiation dermatitis, but more research is needed.
2 citations
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August 2008 in “Oncotarget” Apoptosis in hair follicles spreads through cell death signals, with stem cells slowing the process.
February 2024 in “BioMetals” Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.
January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of TET2 increases the risk of skin and oral cancer.
45 citations
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February 2013 in “The Journal of Dermatology” Keratoacanthoma and some squamous cell carcinomas are linked to hair follicles, while others are not.
12 citations
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October 2006 Matriptase imbalance contributes to cancer development and spread.
11 citations
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January 1999 in “Dermatology”
9 citations
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April 2006 in “Experimental and Clinical Endocrinology & Diabetes” A woman's small, unnoticed adrenal mass turned out to be a rare non-Hodgkin's lymphoma, treated successfully with surgery and therapy.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.
56 citations
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August 2011 in “Best Practice & Research Clinical Gastroenterology” Cancer prevention has progressed with successful drugs and vaccines, but challenges remain in understanding genetic changes and improving strategies.
December 2018 in “Dermatologic Surgery” 1 citations
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May 2024 in “Pediatric Blood & Cancer” Trametinib can effectively treat severe kaposiform lymphangiomatosis when other treatments fail.
August 2021 in “Acta Haematologica Polonica” Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.
46 citations
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December 2018 in “Biomedical Optics Express” Raman spectroscopy could effectively guide skin cancer surgery by identifying tumor margins.
July 2023 in “Panacea Journal of Medical Sciences” Chemotherapy often causes skin, hair, and nail problems in cancer patients.
20 citations
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November 2004 in “Archives of Pathology & Laboratory Medicine” A rare benign skin growth called melanocytic matricoma was identified in a 69-year-old man.
49 citations
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October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
1 citations
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September 2021 in “Advances in skin & wound care” SARS-CoV-2 might infect and multiply in skin tissue, possibly aiding in its transmission.
February 2026 in “World Academy of Sciences Journal” Lymphoma should be considered in unusual scalp hair loss cases, as treatment can work but may lead to severe complications.
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Normal cells outcompete and remove mutant cells in the pancreas with the help of the EphA2 receptor.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
March 2010 in “Ejc Supplements” CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.
10 citations
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April 2009 in “Oncology Reports” Bald-headed individuals may need early non-invasive detection for skin changes linked to cancer risk.
July 2002 in “Science Signaling” Modified β-catenin can cause different effects in mouse skin cells, leading to cysts or tumors depending on the cell type.
January 2012 in “Journal of Investigative Dermatology” Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.
1 citations
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February 2023 in “Journal of Cellular Biochemistry” Cardiomyocyte-derived media can inhibit lung cancer cell growth and movement.
October 2024 in “Indian Journal of Dermatology” Early biopsy is crucial for diagnosing rare skin sarcoidosis, improving treatment.
Hedgehog signaling can create new hair follicles but may also cause tumors.
10 citations
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September 1997 in “Molecular carcinogenesis” Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.