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Curtailing Polycystic Ovary Syndrome: A Review of International Evidence-Based Guidelines and Implications

research Curtailing PCOS

43 citations , October 2019 in “Pediatric Research”

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

research Metabolomic biomarkers in women with polycystic ovary syndrome: a pilot study

43 citations , July 2012 in “Molecular human reproduction”

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

$Long-Term Treatment of Refractory Hypertensive Patients With Minoxidil$

research Long-Term Treatment of Refractory Hypertensive Patients With Minoxidil

43 citations , May 1978 in “JAMA”

Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.

research Evidence-based approach to cutaneous hyperandrogenism in women

42 citations , July 2015 in “Journal of The American Academy of Dermatology”

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

research Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride

40 citations , November 2020 in “JAMA Dermatology”

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

research MINOXIDIL: HOPE FOR THE BALD?

40 citations , May 1987 in “The Lancet”

Minoxidil helps some bald men, but most lose hair again when stopping.

research Management of tinea capitis in childhood

38 citations , July 2010 in “Clinical, cosmetic and investigational dermatology”

To treat tinea capitis in children, oral antifungal medication is necessary, with newer drugs offering shorter treatment times than the traditional griseofulvin.

research Surrogate end-points or primary outcomes in clinical trials in women with polycystic ovary syndrome?

38 citations , June 2004 in “Human Reproduction”

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

research Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

37 citations , September 2018 in “Psychoneuroendocrinology”

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

research Hypertensive crisis associated with St. John’s Wort

37 citations , April 2002 in “The American Journal of Medicine”

St. John's Wort can cause dangerous high blood pressure if taken with certain foods.

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