research Specific interpretation of hair concentrations in 2 fatal metformin intoxication cases
Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.
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300-330 / 1000+ results research Atomic Spectroscopy Analysis of Heavy Metals in Plants
The plants are safe from heavy metal toxicity.
research Review of Cardiovascular Findings in Humans Treated with Minoxidil
Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.
research Embryo‐Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903 , a Novel Potassium‐Competitive Acid Blocker, in Pregnant Rats
YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.
research Androgenic Effects on Ventricular Repolarization
ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
research Clinical Management of Cutaneous Adverse Events in Patients on Chemotherapy: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology
Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.
research Exploring the Potential Routine Use of Electronic Healthcare Record Data to Strengthen Early Signal Assessment in UK Medicines Regulation: Proof-of-Concept Study
Using electronic health records can help identify drug side effects but has some limitations.
research Heart failure associated with minoxidil intoxication in a cat
Minoxidil exposure can cause heart failure in cats.
research Minoxidil: right atrial cardiac pathology in animals and in man.
Minoxidil may cause heart issues in animals and humans.
research Epicardial Fat Thickness in Children with Classic Congenital Adrenal Hyperplasia
Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
research 1300 Blood plasma levels of heart disease biomarker cardiac troponin I are significantly increased in alopecia areata affected individuals
People with alopecia areata have higher levels of a heart disease marker in their blood.
research Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I
People with alopecia areata have higher levels of a heart disease marker than those without hair loss.
research A disproportionality analysis of adverse events caused by pexidartinib from the FDA adverse event reporting system
Pexidartinib often causes liver issues and fatigue, especially in women.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
research Cardiac tamponade due to minoxidil use: a case report and review of the literature
Minoxidil can cause life-threatening heart complications, so careful monitoring is essential.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Evaluation of Potential Toxicity of Calotropis gigantea Leaf Extract on Danio rerio: Bioactive Compounds, Oxidative Stress and Histological Toxicity Analysis
Calotropis gigantea leaf extract causes significant tissue damage and stress in fish.
research Cardiac Amyloidosis and Aortic Stenosis: When to Consider it and How to Treat it?
When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.
research Estimation of biological heart age using cardiovascular magnetic resonance radiomics
Obesity and lifestyle strongly affect heart aging.
research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.
research Research landscapes and knowledge structure of cardiac xenotransplantation: A bibliometric analysis
Cardiac xenotransplantation is moving towards clinical use with growing research and collaboration.
research Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system
Paternal drug exposure can harm fertility, pregnancy outcomes, and offspring health, with specific drugs linked to various reproductive issues.
research Epicardial fat thickness in children with classic congenital adrenal hyperplasia
Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
research Prediction of gain-of-function and loss-of-function mutations using Combined Annotation Dependent Depletion (CADD)
C-scores can help predict gain-of-function and loss-of-function mutations.
research Skin toxicity of anti‐cancer therapy
Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
research Exploring in vitro markers of potency of extracellular vesicles from cardiosphere-derived cells in the treatment of cardiac ageing
Potent extracellular vesicles from cardiosphere-derived cells can improve heart health and other functions in aging.
research Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood
Excess maternal androgens can cause heart problems in offspring.
research Chemotherapy-induced toxicity—a secondary effect caused by released DNA?
Chemotherapy toxicity might be reduced by using DNA neutralizing agents.
research LB1101 Evaluating the cardiovascular safety of low-dose oral minoxidil in patients with non-scarring alopecia: A retrospective cohort study
Low-dose oral minoxidil is safe for the heart in the short term for hair loss patients.
research STRESS AND AGING*
Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.