194 citations
,
March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.
42 citations
,
July 2012 in “PLOS ONE” Estrogen can temporarily slow down hair growth but this can be reversed.
130 citations
,
January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
58 citations
,
October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
28 citations
,
May 2012 in “Veterinary Dermatology” Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.
23 citations
,
July 1982 in “International Journal of Dermatology” The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.
August 2011 in “Planta Medica” 4-O-methylhonokiol from Magnolia Officinalis may promote hair growth by interfering with TGF-β1 effects in skin cells.
57 citations
,
November 1987 in “Pediatric Dermatology” Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.
38 citations
,
October 1988 in “Clinics in Dermatology” Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.
29 citations
,
July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
2 citations
,
June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
224 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
169 citations
,
May 2006 in “Genes & Development” Keratin 17 is crucial for normal hair growth by regulating hair cycle transitions with TNFα.
155 citations
,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
112 citations
,
July 1998 in “Journal of Investigative Dermatology” Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
109 citations
,
December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
71 citations
,
January 2019 in “International journal of biological sciences” Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
61 citations
,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
58 citations
,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
54 citations
,
September 2012 in “Dermatologic Clinics” Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.
51 citations
,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
46 citations
,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
30 citations
,
October 2021 in “Scientific Reports” Inhibiting glycogen metabolism can promote hair growth.
28 citations
,
September 1998 in “Medical Clinics of North America” Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.
24 citations
,
May 2022 in “BMC Veterinary Research” lncRNAs play a key role in hair follicle development, affecting cashmere quality and yield.
19 citations
,
May 2004 in “The American Journal of Dermatopathology” The research found that a specific gene mutation causes fewer hair follicles and disrupted hair growth cycles, leading to thin and short hair in people with Hypotrichosis with Juvenile Macular Dystrophy.