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Green Formulation of Spironolactone Loaded Chitosan Coated Nano Lipid Carrier for Treatment of Acne Vulgaris: A Randomized Double-Blind Clinical Trial

research Green formulation of spironolactone loaded chitosan coated nano lipid carrier for treatment of acne vulgaris: a randomized double-blind clinical trial

8 citations , September 2023 in “Advanced Pharmaceutical Bulletin”

Chitosan-coated spironolactone nano carriers effectively treat acne without side effects.

research Advanced Skin Antisepsis: Application of UVA-Cleavable Hydroxyethyl Starch Nanocapsules for Improved Eradication of Hair Follicle-Associated Microorganisms

1 citations , February 2023 in “Pharmaceutics”

New UVA-responsive nanocapsules effectively kill microorganisms in hair follicles when activated by light.

research Pantolactams as androgen receptor antagonists for the topical suppression of sebum production

5 citations , September 2011 in “Bioorganic & Medicinal Chemistry Letters”

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment

research Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment

December 2023 in “Journal of Medicinal Chemistry”

A new topical treatment for hair loss shows strong hair growth effects with low toxicity.

Cefazolin-Loaded Double-Shelled Hollow Mesoporous Silica Nanoparticles/Polycaprolactone Nanofiber Composites: A Delivery Vehicle for Regenerative Purposes

research Cefazolin-Loaded Double-Shelled Hollow Mesoporous Silica Nanoparticles/Polycaprolactone Nanofiber Composites: A Delivery Vehicle for Regenerative Purposes

6 citations , April 2022 in “Advanced Pharmaceutical Bulletin”

Cefazolin-loaded nanoparticles in nanofibers can help heal wounds and support regeneration.

research Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins

June 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Combining finasteride with dimethyl-β-cyclodextrin improves its absorption and bioavailability.

research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen

9 citations , January 2017 in “Organic Process Research & Development”

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

New Ethanol and Propylene Glycol Free Gel Formulations Containing a Minoxidil-Methyl-Beta-Cyclodextrin Complex as Promising Tools for Alopecia Treatment

research New ethanol and propylene glycol free gel formulations containing a minoxidil-methyl-β-cyclodextrin complex as promising tools for alopecia treatment

18 citations , March 2014 in “Drug Development and Industrial Pharmacy”

New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.

research Calcitriol ointment in the treatment of facial, hairline and retroauricular chronic plaque psoriasis

3 citations , January 1996 in “Journal of Dermatological Treatment”

The ointment is a safe, effective, and well-tolerated treatment for certain types of psoriasis.

research Targeted skin delivery of topically applied drugs by optimised formulation design

2 citations , January 2016

Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.

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