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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Reducing miR-361-5p boosts hair growth in cashmere goats by activating stem cells.

CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.

A specific genetic trait in tumor cells is linked to longer survival without disease in certain lymphoma patients.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

FoxN1 gene is crucial for proper thymus structure and normal skin appearance.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

Changing CDK4 levels affects the number of stem cells in mouse hair follicles.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.

BBS7 is essential for healthy gums by supporting cell function and blood flow.

Antizyme slows skin tumor growth by reducing cell growth in mice.

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Patched1 helps prevent tumors by controlling cell growth.

Notch1 signaling is impaired in hidradenitis suppurativa, affecting skin and hair cells.

Injury boosts normal skin cell growth, reducing cancer cell advantage.

Foxn1 helps skin cells mature by controlling a specific protein's activity.

A humanized IL-2 fusion protein boosts T regulatory cells and helps control hair loss in Alopecia Areata.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.