278 citations
,
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156 citations
,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
118 citations
,
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106 citations
,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
80 citations
,
April 2011 in “Plant physiology” White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
76 citations
,
December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
73 citations
,
June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
59 citations
,
June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
54 citations
,
October 2024 in “Nature Communications” Molybdenum oxide nanozymes can effectively treat and monitor acute kidney injury by reducing oxidative stress.
52 citations
,
November 2009 in “International journal of gynaecology and obstetrics” High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
52 citations
,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
47 citations
,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
45 citations
,
January 2020 in “Pharmaceutical Biology” Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
40 citations
,
January 2017 in “Intestinal Research” Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.
37 citations
,
October 2006 in “Steroids” New sulfur-containing steroid analogs show promise for more targeted medical treatments.
30 citations
,
January 2016 in “Journal of Pharmaceutical and Biomedical Analysis” The research found different metabolism changes in PCOS patients and suggested new potential markers for diagnosing PCOS with or without insulin resistance.
27 citations
,
September 2000 in “JAMA” The document suggests changing medical education to balance generalists and specialists, focusing on patient needs.
24 citations
,
November 1978 in “Biochemistry” α-type filaments in guinea pig hair follicles have unique structural features.
23 citations
,
July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
23 citations
,
July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
22 citations
,
March 2020 in “Cosmetics” Nanotechnology improves minoxidil treatment for hair loss.
19 citations
,
March 2021 in “Obesity surgery” Many people experience hair loss after weight loss surgery, especially younger women, and it's linked to lower levels of zinc, folic acid, and ferritin.
19 citations
,
January 2014 in “International Journal of Medical Sciences” Abnormal activation of hair follicle stem cells and Wnt/β-catenin signaling contributes to sebaceous neoplasms.
18 citations
,
January 1999 in “CNS Drugs” Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.
16 citations
,
May 1998 in “International Journal of Dermatology” Stress hormones like cortisol may trigger psoriasis flare-ups.
15 citations
,
January 2019 in “International Journal of Women's Dermatology” Early treatment helps stop hair loss in women of color.
15 citations
,
January 2018 in “Acta dermato-venereologica” Skin treatment can lower life quality for patients with skin conditions.
14 citations
,
January 2021 in “Cureus” The AndroCoV Clinical Scoring is a quick, accurate, and free tool for diagnosing COVID-19.
13 citations
,
September 2020 in “International Journal of Molecular Sciences” PRP therapy and minoxidil combo works best for male hair loss.