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Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

Targeting TCR-Vβ2 in cutaneous T cell lymphoma shows promise for safer, more specific treatment.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Alopecia areata involves unique activation of certain immune cells.

Activating certain hair follicle cells could prevent hair loss from cancer treatments.

Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

IL-18 signaling helps mature Tregs move into the thymus.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

IL-18 signaling helps mature Tregs move into the thymus.

Certain CD8+ T cells attack hair follicles in alopecia areata, suggesting they could be targeted for treatment.

Hair follicle stem cells have greater longevity and adhesion, while transit-amplifying cells are more mobile.

Boosting certain cell signals can prevent hair loss from cancer treatments.

Amotosalen-treated donor T-cells can prevent late CMV infection after bone marrow transplants.

CD271 is crucial for maintaining healthy skin and preventing inflammation.

The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.

Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.

CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.

Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.

Expanding regulatory T cells may help treat alopecia areata by reducing harmful immune cells.

CXCR2 in skin cells promotes tumor growth.

Activating certain cells in hair follicles can prevent hair loss caused by cancer treatments.