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H3K9me3 Methyltransferase SETDB1 Controls Retrotransposon Silencing, DNA Methylation, Constitutive Heterochromatin Maintenance and 3D-Chromatin Structure in Epidermal Keratinocytes

research 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

research Several variants on chromosome 10 are associated with coarse hair diameter in Dazu black goats (Capra hircus)

3 citations , January 2025 in “Animal Genetics”

Variants on chromosome 10 affect hair thickness in Dazu black goats.

Cedrol Restricts the Growth of Colorectal Cancer In Vitro and In Vivo by Inducing Cell Cycle Arrest and Caspase-Dependent Apoptotic Cell Death

research Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death

January 2022 in “International Journal of Medical Sciences”

Cedrol may be an effective treatment for colorectal cancer.

Management of Congenital Adrenal Hyperplasia During Pregnancy

research Management of CAH during pregnancy

29 citations , December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity”

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

research [An immunohistochemical study on the normal human anagen hair and hair follicle using anti-hair keratin monoclonal antibodies (HKN-5, HKN-6, HKN-7 and HKN-8)].

October 1985 in “PubMed”

research The effectiveness of acaricidal drugs in bovine psoroptosis

April 2024 in “Meždunarodnyj vestnik veterinarii”

Deltsid 7.5 is the most effective treatment for bovine psoroptosis.

research An Australian family with macular dystrophy linked to autosomal recessive alopecia universalis

3 citations , February 2001 in “British journal of ophthalmology”

An Australian with rare hair loss and eye conditions had a gene linked to both, not seen together before.

research Immunization by Application of DNA Vaccine onto a Skin Area Wherein the Hair Follicles Have Been Induced into Anagen-onset Stage

20 citations , August 2007 in “Molecular therapy”

Applying a DNA vaccine to skin with active hair growth boosts immune response and protection against anthrax in mice.

research Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome

January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

research Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeat

36 citations , July 2014 in “Neuromuscular Disorders”

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

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