Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
43 citations
,
October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
1113 citations
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
159 citations
,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
131 citations
,
March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
35 citations
,
March 2014 in “British Journal of Dermatology” Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
29 citations
,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
14 citations
,
June 2021 in “Expert Opinion on Therapeutic Patents” New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
11 citations
,
June 2016 in “npj Regenerative Medicine” The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
6 citations
,
September 2024 in “Frontiers in Physiology” Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
4 citations
,
February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
3 citations
,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
2 citations
,
July 2021 in “Biochemical and Biophysical Research Communications” CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.
Removing SIX1 in fat cells reduces skin fibrosis.
February 2024 in “Frontiers in physiology” Hair follicle stem cells help skin heal and grow during stretching.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
October 2023 in “Advancement in yoga and physical therapy” More research is needed before using brown fat to treat polycystic ovary syndrome.
October 2023 in “Frontiers in endocrinology” Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
March 2021 in “Research Square (Research Square)” The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
112 citations
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
87 citations
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July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
55 citations
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January 2007 in “Climacteric” Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.
47 citations
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January 2015 in “Dermatology” The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
21 citations
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January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
18 citations
,
January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
11 citations
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June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.