research Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function
Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
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research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function
Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
research In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
research Zinc Deficiency: The Association with Vitamin B12 in People of Different Ages
Zinc deficiency might affect vitamin B12 levels.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Wound Induced Hair Neogenesis – A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Keratins and skin disease
Keratin mutations cause skin diseases and could lead to new treatments.
research Aging hair follicles rejuvenated by transplantation to a young subcutaneous environment
Old hair follicles grew better when moved to a young environment.
research Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle
Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
research Terrestrial vertebrates have two keratin gene clusters; striking differences in teleost fish
Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
research The organization of the keratin I and II gene clusters in placental mammals and marsupials show a striking similarity
Keratin gene clusters in humans and marsupials are similarly organized.
research Application of mesenchymal stem cells for anti-senescence and clinical challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology
MSC-derived exosomes may help in skin repair and regeneration.
research Combination of the stromal vascular fraction and platelet-rich plasma accelerates the wound healing process: pre-clinical study in a Sprague-Dawley rat model
Combining SVF and PRP speeds up wound healing.
research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats
HGF-modified hair follicle stem cells help brain recovery after injury in rats.
research Chitosan stimulates root hair callose deposition, endomembrane dynamics, and inhibits root hair growth
Chitosan affects root hair growth and callose deposition based on its concentration.
research The Roles of EDA2R in Ageing and Disease
EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.
research Hair growth stimulated by allogenic adipose-derived stem cells supplemented with ATP in a mouse model of dihydrotestosterone-induced androgenetic alopecia
Combining stem cells with ATP significantly boosts hair regrowth in mice with hair loss.
research Restoration of follicular β-catenin signaling by mesenchymal stem cells promotes hair growth in mice with androgenetic alopecia
Stem cells from umbilical cords can help regrow hair in mice with hair loss.
research An optimized force-triggered density gradient sedimentation method for isolation of pelage follicle dermal papilla cells from neonatal mouse skin
New method efficiently isolates hair growth cells from newborn mouse skin.
research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research Current Advanced Therapies Based on Human Mesenchymal Stem Cells for Skin Diseases
Human mesenchymal stem cells show promise for treating skin diseases, but more research is needed to improve treatments.
research Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling
Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.
research An Autophagy-Related Kinase Is Essential for the Symbiotic Relationship between Phaseolus vulgaris and Both Rhizobia and Arbuscular Mycorrhizal Fungi
A specific enzyme is crucial for the bean plant's relationship with certain beneficial soil bacteria and fungi.
research Intravenous Transplantation of Human Hair Follicle-Derived Mesenchymal Stem Cells Ameliorates Trabecular Bone Loss in Osteoporotic Mice
Human hair follicle stem cells can help treat bone loss in osteoporosis.
research Dietary Vitamin A Impacts Refractory Telogen
Eating too much or too little vitamin A can cause hair loss.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.