9 citations
,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
6 citations
,
January 2023 in “International journal of molecular sciences” Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.
3 citations
,
February 2025 in “Frontiers in Cell and Developmental Biology” Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.
3 citations
,
June 2021 in “Frontiers in genetics” The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
1 citations
,
January 2025 in “Genes & Diseases” Understanding T cells and signaling pathways can lead to better treatments for hair loss.
1 citations
,
January 2023 in “Burns & Trauma” Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
72 citations
,
January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
36 citations
,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
30 citations
,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
14 citations
,
May 2017 in “Cell metabolism” Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.
11 citations
,
October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
106 citations
,
July 2013 in “Advances in wound care” UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.
48 citations
,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
40 citations
,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
22 citations
,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
12 citations
,
March 2019 in “Lasers in Surgery and Medicine” Low-level laser therapy improves hair growth and dermal papilla cell function.
6 citations
,
July 2025 in “Advanced Materials” Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.
2 citations
,
November 2025 in “Pharmaceutics” Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
1 citations
,
January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
1 citations
,
November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
510 citations
,
August 2006 in “Endocrinology” The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
401 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
294 citations
,
February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
249 citations
,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.