research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
Search
for
Sort by
Research
420-450 / 1000+ results research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair
β-catenin in the dermal papilla is crucial for normal hair growth and repair.
research Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia
Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research CD34 + cell–derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis
CD34+ cells help heal damaged limbs by promoting blood vessel growth.
research Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research Cell cycle controls long-range calcium signaling in the regenerating epidermis
Calcium signaling in skin cells is crucial for communication and regeneration.
research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata
Non-immune factors play a significant role in alopecia areata.
research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone
The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
research Flightless I Expression Enhances Murine Claw Regeneration Following Digit Amputation
Mice with more Flightless I protein grew back their claws better after amputation.
research Keratin function and regulation in tissue homeostasis and pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Combination of an engineered Lactococcus lactis expressing CXCL12 with light‐emitting diode yellow light as a treatment for scalded skin in mice
The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.
research A probabilistic Boolean model on hair follicle cell fate regulation by TGF-β
TGF-β and TNF influence hair follicle cell fate, with TNF being more effective in triggering cell death.
research RSPO1, a potent inducer of pancreatic β cell neogenesis
RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.
research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets
Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.
research THBS4 promotes hair regeneration by inducing dermal mechanical niche adaptation
THBS4 helps hair grow by activating hair follicle stem cells.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
research Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics
Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
research Comparative Morphological Characterization of Skin after Subcutaneous Application of Hyaluronic Acid and Polycaprolactone in Rats: Establishment of an Experimental Model
Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.
research Decision letter: ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomas
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
research Hairless: A nuclear receptor corepressor essential for skin function
The Hairless gene is crucial for healthy skin and hair growth.
research Faculty Opinions recommendation of Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche.
Stem cell niche exit in C. elegans is influenced by Sh1 cell membrane protrusions.
research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
research Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle
Sox10 is important for hair follicle development and hair growth cycles.
research Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors
A female dog with mixed male and female traits was treated successfully with surgery.
research Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure
Cell-free fat extract may boost IVF success in older women with past failures.
research 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla
The research identified specific genes that are active in the cells crucial for hair growth.
research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair
The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.