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Artepillin C and Other Herbal PAK1-Blockers: Effects on Hair Cell Proliferation and Related PAK1-Dependent Biological Function in Cell Culture

research Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture

23 citations , November 2015 in “Phytotherapy Research”

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways

research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways

24 citations , September 2005 in “Journal of Cellular Biochemistry”

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

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Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines

11 citations , September 2020 in “OncoTargets and Therapy”

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

A 5α-Reductase Inhibitor, Finasteride, Increases Differentiation and Proliferation of Embryonal Carcinoma Cell-Derived Neural Cells

research A 5α-reductase inhibitor, finasteride, increases differentiation and proliferation of embryonal carcinoma cell-derived-neural cells

4 citations , September 2010 in “Medical Hypotheses”

CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis

research CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis

3 citations , April 2014 in “Journal of Dietary Supplements”

CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.

TCL1 Transgenic Mouse Model as a Tool for the Study of Therapeutic Targets and Microenvironment in Human B-Cell Chronic Lymphocytic Leukemia

research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

38 citations , January 2016 in “Cell Death and Disease”

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

research Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes

6 citations , December 2017 in “Molecular Medicine Reports”

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

research Co-opting Developmental Signaling Pathways to Promote Wound Healing

1 citations , January 2018 in “Recent clinical techniques, results, and research in wounds”

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

research YAP and TAZ are essential for basal and squamous cell carcinoma initiation

76 citations , June 2018 in “EMBO Reports”

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

research Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration

10 citations , November 2022 in “Protein & Cell”

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

research 4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling

5 citations , February 2017 in “Biomolecules & Therapeutics”

4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.

research 1376 Dermal white adipose tissue enhances proliferation, pigmentation and hair shaft elongation in human hair follicles ex vivo

April 2018 in “Journal of Investigative Dermatology”

Fat under the skin can help hair grow longer, darker, and increase cell growth.

research Stem Cell Competition for Niche Occupancy: Emerging Themes and Mechanisms

13 citations , February 2010 in “Stem Cell Reviews and Reports”

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway

113 citations , September 2005 in “Journal of Investigative Dermatology”

Applying a special compound can promote hair growth without harmful side effects.

research The Harmonies Played by TGF-β in Stem Cell Biology

156 citations , December 2012 in “Cell Stem Cell”

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

133 citations , May 2016 in “Cell Host & Microbe”

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures

research Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures

61 citations , September 2010 in “Genomics”

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate

57 citations , March 2018 in “International Journal of Molecular Sciences”

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

research AtCSLD3 and GhCSLD3 mediate root growth and cell elongation downstream of the ethylene response pathway in Arabidopsis

35 citations , December 2017 in “Journal of Experimental Botany”

AtCSLD3 and GhCSLD3 genes enhance root growth and cell elongation in plants.

Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix

research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix

30 citations , April 2017 in “European Journal of Cell Biology”

CIP/KIP proteins help stop cell division and support hair growth.

From Basal Cell Carcinoma Morphogenesis to Alopecia Induced by Hedgehog Inhibitors: Connecting the Dots

research From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots

17 citations , June 2017 in “British Journal of Dermatology”

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

research Hair follicle mesenchymal stem cell exosomal lncRNA H19 inhibited NLRP3 pyroptosis to promote diabetic mouse skin wound healing

13 citations , February 2023 in “Aging”

A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.

research Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice

10 citations , August 2018 in “Experimental Dermatology”

Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.

Intrinsic Activation of Cell Growth and Differentiation in Ex Vivo Cultured Human Hair Follicles by a Transient Endogenous Production of ROS

research Intrinsic activation of cell growth and differentiation in ex vivo cultured human hair follicles by a transient endogenous production of ROS

9 citations , March 2019 in “Scientific reports”

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

research Wound Healing Effect of Supercritical Carbon Dioxide Datura metel L. Leaves Extracts: An In Vitro Study of Anti-Inflammation, Cell Migration, MMP-2 Inhibition, and the Modulation of the Sonic Hedgehog Pathway in Human Fibroblasts

6 citations , July 2023 in “Plants”

Datura metel leaf extracts help heal wounds effectively.

research The Potential of a Hair Follicle Mesenchymal Stem Cell-Conditioned Medium for Wound Healing and Hair Follicle Regeneration

6 citations , April 2020 in “Applied sciences”

Hair growth medium helps heal wounds and regrow hair in mice.

research STAT3 Partly Inhibits Cell Proliferation via Direct Negative Regulation of FST Gene Expression

3 citations , June 2021 in “Frontiers in genetics”

The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.

Thymosin β4 Identified by Transcriptomic Analysis from Hair Follicle Anagen to Telogen Promotes Proliferation of Secondary Hair Follicle Dermal Papilla Cells in Albas Cashmere Goat

research Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat

3 citations , March 2020 in “International Journal of Molecular Sciences”

Thymosin β4 helps increase hair growth in Cashmere goats.

research Injectable platelet rich fibrin facilitates hair follicle regeneration by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity

2 citations , October 2021 in “Experimental Cell Research”

Injectable platelet-rich fibrin helps hair growth by boosting key cell functions.

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L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes

2 citations , August 2020 in “Clinical, Cosmetic and Investigational Dermatology”

The hair-growth formula with L-cystine helps protect and grow hair cells.

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