5 citations
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January 2021 in “Inflammatory Bowel Diseases” Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.
April 2019 in “Journal of Investigative Dermatology” Low-level laser therapy helps hair growth and reduces hair loss with few side effects.
37 citations
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June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
1 citations
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September 2012 in “Expert Review of Endocrinology & Metabolism” Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
117 citations
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March 2013 in “Journal of the European Academy of Dermatology and Venereology” No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
21 citations
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December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
4 citations
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August 2018 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” There is an urgent need for better treatments for hair loss caused by chemotherapy.
January 2009 in “Indian Journal of Plastic Surgery” Surgical methods for hair loss due to scarring should be chosen based on the size, location, and shape of the area, with most patients seeing good results.
139 citations
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August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
129 citations
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January 2007 in “Otology & Neurotology” Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
4 citations
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January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
26 citations
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January 1994 in “Hormone and Metabolic Research” Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.
178 citations
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August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
1265 citations
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October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
203 citations
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December 2004 in “Journal of The American Academy of Dermatology” Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
84 citations
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June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
39 citations
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April 2024 in “Frontiers in Endocrinology” New treatments aim to improve thin endometrium to help more couples with infertility.
39 citations
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January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
34 citations
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July 2011 in “Journal of Dermatological Treatment” Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.
34 citations
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April 2009 in “Expert Opinion on Pharmacotherapy” Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
28 citations
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October 1998 in “Baillière's clinical endocrinology and metabolism” Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
21 citations
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August 2003 in “Seminars in oncology nursing” Nurses are crucial in managing chemotherapy side effects for ovarian cancer patients to improve their quality of life.
18 citations
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June 2010 in “Current medicinal chemistry” Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.
17 citations
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June 2018 in “Sexual Medicine Reviews” The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
14 citations
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January 2017 in “Skin appendage disorders” Simvastatin/ezetimibe did not effectively treat severe alopecia areata and caused side effects in some patients.
9 citations
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January 2007 in “Endocrine Practice” A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
8 citations
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January 2020 in “Plastic and Aesthetic Nursing” The article concludes that different types of hair loss require specific treatments and psychological support is important.
6 citations
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February 1974 in “The BMJ” The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.