research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
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research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Establishment of an in vitro organoid model of dermal papilla of human hair follicle
Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Differential gene expression analysis between anagen and telogen of Capra hircus skin based on the de novo assembled transcriptome sequence
Signaling pathways are crucial for hair growth in goats.
research An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Thymosin β4 Promotes Dermal Healing
Thymosin β4 helps improve skin healing and reduce scarring.
research Engineering the niche for hair regeneration — A critical review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation
N-WASP is essential for healthy skin and preventing inflammation.
research Chitosan/LiCl composite scaffolds promote skin regeneration in full-thickness loss
Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
research Alopecia as a rare but distinct manifestation of pemphigus vulgaris
Hair loss is a rare but recognized symptom of pemphigus vulgaris, with patients usually regrowing hair after treatment.
research ILK modulates epithelial polarity and matrix formation in hair follicles
ILK is essential for proper hair follicle development and structure.
research Peripheral blood gene expression in alopecia areata reveals molecular pathways distinguishing heritability, disease and severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia
Genomic approach finds new possible treatments for hair loss.
research Quantitative proteomic analysis of dermal papilla from male androgenetic alopecia comparing before and after treatment with low‐level laser therapy
Low-level laser therapy improves hair growth and dermal papilla cell function.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Cutaneous transcriptome analysis in NIH hairless mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research ELL Facilitates RNA Polymerase II–Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.
research A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes
Activated β-catenin affects hair growth and skin thickness, and changes are reversible.
research 642 Uncovering the role of UV exposure history and genetics in determining skin sun damage
UV photography can help identify people at higher risk for skin cancer, and male pattern baldness at age 45 is linked to a higher risk of certain skin cancers.
research Positive Impact of Fish Oil on Diabetic and Hypercholestrolemic Skin Disorders
Fish oil improves skin health in people with diabetes and high cholesterol.
research Regenerative medicine in aesthetic surgery: Hope or hype?
Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.
research MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells
MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
research In focus in HCB
The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research Human hair keratin hydrogel : fabrication, characterization and application
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.