research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
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research Bioengineering skin using mechanisms of regeneration and repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research 4D polycarbonates via stereolithography as scaffolds for soft tissue repair
4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.
research Physiologic functions of PP2A: Lessons from genetically modified mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Antioxidants in dermatology
Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
research The role of macrophages in skin homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
research Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles
Platelet-derived chemokines help muscle healing by attracting neutrophils to injured areas.
research Cicatricial alopecia
Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
research Pathophysiology of the burn scar
Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
research 280 Investigation into the role of HIF-1A stabilisation in hair follicle metabolism
Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
research Cytoskeletal Regulation of Dermal Regeneration
Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice—A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Effect of high-fructose diet on the renal cortex of adult male albino rats
High-fructose diets can cause irreversible kidney damage.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice
γδ T cells adapt uniquely to different tissues in mice.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Tratamiento con Exosomas en Alopecia Areata Difusa Refractaria en Paciente Pediátrico: Reporte de Caso
Exosomes helped regrow hair in a 14-year-old with difficult-to-treat alopecia.
research Restoration of hair growth with topical diphencyprone in mouse and rat models of alopecia areata
Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
research The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair
Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
research Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Mechanical stretch induces hair regeneration through the alternative activation of macrophages
Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
research The blastema and epimorphic regeneration in mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration
Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.