April 2018 in “Journal of Investigative Dermatology” Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
April 2018 in “Journal of Investigative Dermatology” Nicotinic acid reduces excessive oil production in skin cells by activating a specific receptor, which could help treat acne.
April 2018 in “Journal of Investigative Dermatology” The role of γδT-cells in causing alopecia areata remains unclear.
April 2018 in “Journal of Investigative Dermatology” Mint water extract boosts protective enzymes in skin cells.
April 2018 in “Journal of Investigative Dermatology” Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
May 2017 in “InTech eBooks” Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.
January 2017 in “NASA Technical Reports Server (NASA)” Early changes in skin gene expression can predict later bone mass loss after radiation exposure.
April 2016 in “Journal of Investigative Dermatology” Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
April 2016 in “Journal of Investigative Dermatology” Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” Diabetic patients' stem cells make vascular grafts more prone to clots, but new methods may improve grafts.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
January 2008 in “Springer eBooks” Thyroid hormone may be useful for treating various skin conditions and needs more research.
April 2003 in “Experimental Dermatology” The workshop highlighted the genetic links and psychological impacts of hair loss and skin disorders.
January 1998 in “Lasers in Surgery and Medicine” Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.
1 citations
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January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
144 citations
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August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
58 citations
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October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
54 citations
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November 2001 in “Urology” The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.
48 citations
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June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
42 citations
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May 2013 in “Oral Diseases” Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
29 citations
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March 2015 in “Journal of Investigative Dermatology” Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.
26 citations
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December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
19 citations
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January 2015 in “Scientific Reports” GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.
11 citations
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March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.