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Did you mean Cellular Retinoic Acid-Binding Protein 2?

GlossaryCellular Retinoic Acid-Binding Protein 2

protein that regulates retinoic acid's effects in cells

Cellular Retinoic Acid-Binding Protein 2 (CRABP2) is a protein that binds to retinoic acid, a derivative of vitamin A, and helps regulate its availability and activity within cells. This protein plays a crucial role in cell growth, differentiation, and apoptosis, making it important in processes like skin health and hair growth.

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research Immunolocalization of Enzymes, Binding Proteins, and Receptors Sufficient for Retinoic Acid Synthesis and Signaling During the Hair Cycle

48 citations , March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

Increased Retinol-Binding Protein 4 and Anti-RBP4 Antibody in Alopecia Areata

research Increased retinol‐binding protein (RBP) 4 and anti‐RBP4 antibody in alopecia areata

6 citations , June 2011 in “British Journal of Dermatology”

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

research Assessment of retinol-binding protein 4 in patients with alopecia areata and androgenetic alopecia

September 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Higher RBP4 levels found in people with two types of hair loss.

Serum Levels of Retinol-Binding Protein 4 and Adiponectin in Women with Polycystic Ovary Syndrome: Associations with Visceral Fat but No Evidence for Fat Mass-Independent Effects on Pathogenesis in This Condition

research Serum Levels of Retinol-Binding Protein 4 and Adiponectin in Women with Polycystic Ovary Syndrome: Associations with Visceral Fat But No Evidence for Fat Mass-Independent Effects on Pathogenesis in This Condition

44 citations , April 2008 in “The Journal of Clinical Endocrinology & Metabolism”

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

research Retinol-binding protein 4, leptin, and insulin resistance in idiopathic hirsutism and hirsute women with polycystic ovary syndrome

1 citations , May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

research Cellular Senescence and Aging in Myotonic Dystrophy

4 citations , February 2022 in “International Journal of Molecular Sciences”

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome

research Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome

19 citations , March 2007 in “Journal of diabetes science and technology”

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations , April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

research Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling

84 citations , September 2008 in “Developmental biology”

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Comparative Transcriptome Profiling of Hair Follicles from Forest Musk Deer at Different Stages

research Comparative transcriptome profiling of hair follicles from forest musk deer (Moschus berezovskii) at different stages

November 2022 in “Research Square (Research Square)”

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.

research Co-opting Developmental Signaling Pathways to Promote Wound Healing

1 citations , January 2018 in “Recent clinical techniques, results, and research in wounds”

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument

19 citations , April 2015 in “Developmental Dynamics”

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

research Endogenous retinoids in the hair follicle and sebaceous gland

50 citations , September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids”

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

research Estrogen regulates the expression of retinoic acid synthesis enzymes and binding proteins in mouse skin

3 citations , August 2021 in “Nutrition research”

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

research The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells

42 citations , February 2014 in “Stem Cells and Development”

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

research TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model

16 citations , September 2016 in “Neuropharmacology”

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

research Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein

November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Network Analysis Reveals Potential Mechanisms That Determine the Cellular Identity of Keratinocytes and Corneal Epithelial Cells Through the Hox/Gtl2-Dio3 miRNA Axis

research Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis

January 2025 in “Frontiers in Cell and Developmental Biology”

Hox proteins help maintain keratinocyte identity by regulating miRNA expression.

Human Dermal Fibroblasts Show Positive Immunostaining for Neuron and Glia Specific Proteins

research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins

15 citations , December 2015 in “PLoS ONE”

Fibroblasts can be mistaken for neural cells, so functional validation is needed.

research Editorial: Hair Follicle Stem Cell Regeneration in Aging

4 citations , November 2021 in “Frontiers in Cell and Developmental Biology”

Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.

research Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders

20 citations , December 2020 in “Frontiers in Immunology”

The immune processes causing VKH and vitiligo are similar in dogs and humans.