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The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

5-ARI therapy may help prevent prostate cancer progression.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Sebocytes play a key role in controlling androgen levels in human skin.

The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.

Five existing drugs may help fight Swine Acute Diarrhea Syndrome Coronavirus.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Sterculia villosa and Vernonia patula show potential as antioxidants.

A patient with Ivemark syndrome developed mixed type vitiligo after a hepatitis C infection, showing different treatment responses and immune cell involvement in the skin.

Compound 4 is a promising treatment for hair loss with low toxicity.

Surgical excision is the best treatment for SCC, but intralesional cidofovir might be a good alternative.

Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.

Seven genes are highly expressed in both germ-line and hematopoietic stem cells.

5-Aminolevulinic acid can help chicken sperm move better at the right amount.

The compound 4c showed strong potential as an anticancer agent.