42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
June 2025 in “Stem Cell Research & Therapy” Combining stem cells with ATP significantly boosts hair regrowth in mice with hair loss.
1 citations
,
April 2021 in “Journal of Investigative Dermatology” Activating TRPA1 reduces scarring and promotes tissue regeneration.
April 2017 in “Journal of Investigative Dermatology” Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
41 citations
,
November 2013 in “Experimental Dermatology” Leptin, a hormone, is important for starting hair growth.
7 citations
,
January 2017 in “Skin Pharmacology and Physiology” ECOHAIR® lotion is effective and safe for improving hair growth and reducing hair loss.
47 citations
,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
25 citations
,
June 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
17 citations
,
July 1995 in “International Journal of Dermatology” Minoxidil helps prevent hair loss from chemotherapy in rats.
1 citations
,
July 2025 in “MedComm – Biomaterials and Applications” Microneedles show promise for cancer diagnosis and treatment due to their minimally invasive nature and effective drug delivery.
96 citations
,
August 1995 in “Bone” Vitamin D3 is important for bone health and may help treat various diseases beyond bone-related conditions.
61 citations
,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
29 citations
,
February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
March 2024 in “EMBO molecular medicine” Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
January 2026 in “Journal of Contemporary Medicine” Vitamin D may help prevent or reduce hair loss after COVID-19.
6 citations
,
June 2023 in “American Society of Clinical Oncology Educational Book” Cannabis, cryotherapy, and scalp cooling can help improve the quality of life for chemotherapy patients.
18 citations
,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
1 citations
,
May 2024 in “Applied Sciences” Cordyceps militaris is a promising, cost-effective medicinal fungus with health benefits and efficient production methods.
January 2026 in “Supportive Care in Cancer” New cooling caps can help prevent hair loss from chemotherapy in a cost-effective and eco-friendly way.
64 citations
,
July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
5 citations
,
July 2019 in “Investigational new drugs” TLR7-based compounds may help manage chemotherapy-induced hair loss.
March 2024 in “International journal of pharmaceutical chemistry and analysis (Print)” Betulin may help treat hair loss caused by testosterone.
8 citations
,
October 2017 in “Dermatology practical & conceptual” A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.
6 citations
,
August 2001 in “PubMed” The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
2 citations
,
November 2019 in “Skin appendage disorders” Platelet-rich plasma doesn't prevent hair loss from chemotherapy, and mononuclear cells only help against hair loss from one specific chemotherapy drug.
2 citations
,
March 2013 in “Phytotherapy Research” Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
32 citations
,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
20 citations
,
July 2013 in “PLoS ONE” Targeting EGFR may help reduce hair loss from chemotherapy.
6 citations
,
November 2018 in “Antimicrobial agents and chemotherapy (Print)” Fluconazole can cause hair loss, but the exact cause is unknown.
2 citations
,
September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.