research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
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research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research Sensitive Bromatometric Determination Of Finasteride In Pharmaceuticals Based On Complex-Formation Reactions
Two accurate methods were developed to measure finasteride in tablets.
research Twelve‐point scale grading system of scanning electron microscopic examination to investigate subtle changes in damaged hair surface
The 12-point scale is better for evaluating small changes in hair condition after using hair care products.
research Experimental Assessment of 3-<i>meta</i>-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors <i>in silico</i> and <i>in vivo</i> Models
The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
research A fast liquid chromatographic/mass spectrometric screening method for the simultaneous detection of synthetic glucocorticoids, some stimulants, anti‐oestrogen drugs and synthetic anabolic steroids
A quick method effectively detects banned substances in urine.
research Insights on the mechanical behavior of keratin fibrils
Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
research Biodegradable composite from discarded hair keratin and graphene oxide with improved mechanical, thermal and barrier properties: an eco‐friendly solution to waste materials
The keratin-graphene oxide composite is stronger, more heat resistant, and better at blocking gases than pure keratin, offering an eco-friendly use for waste hair.
research 268 Use of ultra-fast one-step CK5 ihc for identifying bcc and scc during mohs surgery
A new one-step test can quickly identify skin cancer during surgery.
research QUESTIONS OF TEACHING MEDICAL BIOCHEMISTRY AS PART OF AN INTEGRATED EDUCATIONAL PROGRAM IN A MEDICAL UNIVERSITY
Integrating medical biochemistry with other subjects improves clinical problem-solving skills.
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Tannic acid modified keratin/sodium alginate/carboxymethyl chitosan biocomposite hydrogels with good mechanical properties and swelling behavior
The hydrogel shows promise for wound healing due to its strong mechanical, antimicrobial, and antioxidant properties.
research In-Situ Tensile Testing of Hair Fibers in An Environmental Scanning Electron Microscope (ESEM)
Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
research Study the Structure and Dynamics of Antifungal Agent Ketoconazole by CSA and Site-Specific Spin-Lattice Relaxation Time Measurements
Ketoconazole's structure and dynamics are linked, aiding antifungal drug development.
research A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin
A small 3D skin model helps study how immune cells move in the skin.
research Hair keratin molecular dynamics studies
Simulations of hair keratin help improve disease treatment and cosmetic products.
research Automated analysis of scanning electron microscopic images for assessment of hair surface damage
A new automated method accurately measures hair damage using microscopic images.
research Simultaneous Quantification of Dexpanthenol and Resorcinol from Hair Care Formulation Using Liquid Chromatography: Method Development and Validation
Researchers created a reliable method to measure dexpanthenol and resorcinol in hair products.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research Two-dimensional electrophoretic analysis of human hair keratins, especially hair matrix proteins
The method effectively analyzes human hair proteins, especially nonfilamentous ones.
research Optimizing finasteride chemoprevention
research Voltammetric sensing of minoxidil using a molecularly imprinted polymer (MIP)-modified carbon paste electrode
A new sensor can detect minoxidil accurately and effectively.
research INTRODUCING OPTICAL MICROSCOPY METHODOLOGY DISPLAYING EMITTED ELECTROMAGNETIC ENERGY OF PRE-CANCEROUS SKIN SQUAMOUS CELL CARCINOMA
The new microscope method helps study energy from pre-cancerous skin cells.
research Forskolin-loaded carboxymethyl chitosan and silk nonofiber hydrogels composite scaffolds improve skin regeneration
Forskolin-loaded hydrogels improve wound healing and skin repair.
research Crystal Structure of Minoxidil
Minoxidil's crystal structure shows two different molecule shapes and nitrogen states.
research Structural studies of two solid steroid compounds
Androsterone and finasteride have different solid forms, with new findings correcting previous errors and identifying a new form.
research A simple method for the demonstration of the iron pigment in human red hair.
research Cutaneous Two-Stage Chemical Carcinogenesis
The method effectively induces skin cancer in mice for studying tumor development.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research Direct access to novel chromeno-pyrimidine-N-oxides via tandem base catalyzed double nucleophilic addition/dehydration reaction
New method makes important drug ingredients more easily without needing extra purification steps.