151 citations
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February 2007 in “International Journal of Dermatology” Alopecia areata causes hair loss, has no cure, and various treatments exist.
149 citations
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July 2002 in “Dermatologic clinics” Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
144 citations
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September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
140 citations
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February 2020 in “Frontiers in Plant Science” RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
139 citations
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February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Transplant success has improved with better immunosuppressive drugs and donor matching.
137 citations
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March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
98 citations
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May 2008 in “British Journal of Dermatology” There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.
94 citations
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July 2020 in “European Journal of Human Genetics” The guidelines ensure accurate genetic testing and reporting for 21-hydroxylase deficiency.
87 citations
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July 2012 in “Expert Review of Clinical Immunology” Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
82 citations
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August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
72 citations
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February 2011 in “The American Journal of Dermatopathology” Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.
65 citations
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January 2013 in “Cochrane library” Some systemic treatments work for nail psoriasis but can have serious side effects.
60 citations
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January 2023 in “Biomaterials Science” PLGA-based microneedles are promising for safe and effective skin delivery of drugs and vaccines.
60 citations
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September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
59 citations
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June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
57 citations
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September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
55 citations
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April 2022 in “Journal of Molecular Medicine” Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
55 citations
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June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
53 citations
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April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
48 citations
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January 2024 in “Immune Network” IL-15 is key for T cell function and could help improve treatments for immune-related diseases.
47 citations
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November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
45 citations
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April 2019 in “Scientific Reports” Higher CO2 levels help a cyanobacterium grow better by boosting photosynthesis and carbon uptake.
45 citations
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January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
43 citations
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February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
39 citations
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March 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
38 citations
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January 2009 in “Journal of Cutaneous Medicine and Surgery” A woman developed hair loss after starting a treatment with adalimumab, suggesting this medication might cause hair loss.
36 citations
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December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
35 citations
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October 2012 in “Dermatologic Clinics” Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.