47 citations
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May 2020 in “Cardiovascular Research” The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
47 citations
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June 2011 in “Movement Disorders” The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
46 citations
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May 2011 in “Movement Disorders” Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
44 citations
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October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
44 citations
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April 2006 in “Expert opinion on drug safety” Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
43 citations
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July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
43 citations
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February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
42 citations
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January 2024 in “Frontiers in Endocrinology” Plant-based drugs are effective and safe alternatives for managing PCOS symptoms.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
42 citations
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July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
41 citations
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June 2010 in “Clinics in Dermatology” Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.
39 citations
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July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
39 citations
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April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
39 citations
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May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
39 citations
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May 2011 in “Movement Disorders” Finasteride may help reduce symptoms in male Tourette syndrome patients.
38 citations
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November 2012 in “Expert Opinion on Drug Safety” Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
38 citations
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July 2021 in “ACS Nano” Microneedles help treat hair loss by improving hair surroundings and promoting growth.
38 citations
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June 2018 in “Plant & cell physiology/Plant and cell physiology” Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
38 citations
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November 2013 in “Journal of The American Academy of Dermatology” Higher BMI links to worse hair loss in Taiwanese men.
36 citations
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June 2021 in “Experimental & Molecular Medicine” Targeting Hedgehog signaling may help treat ligamentum flavum fibrosis.
35 citations
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January 2019 in “Clinics in Dermatology” Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.
35 citations
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October 2017 in “Trends in Molecular Medicine” Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
34 citations
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February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
34 citations
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July 2011 in “International journal of pharmaceutics” Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
31 citations
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June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
30 citations
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August 2021 in “Oncogene” miR-22 helps skin cancer grow and spread by activating specific cell signals.
30 citations
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January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
30 citations
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April 2014 in “Seminars in Reproductive Medicine” Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.
29 citations
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March 2008 in “Postcolonial Studies” The article concludes that the global hair trade is exploitative and reflects complex cultural and economic issues.