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July 2010 in “Advances in Therapy” SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
July 2023 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” Antiandrogens help improve developmental delays caused by valproic acid in rats.
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August 2024 in “Frontiers in Drug Discovery” Drug repurposing is a faster, cheaper way to develop new treatments using existing drugs.
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April 2011 in “Neuropharmacology” 11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
February 2014 in “Revista Argentina de Cardiología” Androgens may increase arrhythmias in Brugada Syndrome, while Finasteride could reduce them.
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September 2000 in “Journal of Medicinal Chemistry” Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
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January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
January 2013 in “Journal of Siberian Medical Sciences” Deer antler products improved hair growth and thickness for people with hair loss.
19 citations
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January 2012 in “Frontiers in Neural Circuits” Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
December 2024 in “African Journal of Biomedical Research” Combining dexmedetomidine and ketamine provides better sedation and pain relief than dexmedetomidine alone.
January 2023 in “Indian Journal of Forensic and Community Medicine” Thallium poisoning is dangerous but treatable with specific medical interventions.
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December 2015 in “Der Urologe” Combining medications is more effective for treating benign prostatic syndrome symptoms.
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February 1979 in “Veterinary Clinics of North America: Small Animal Practice” Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
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August 2016 in “Scientific Reports” Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
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July 2003 in “Annals of the Rheumatic Diseases” Co-trimoxazole successfully treated a girl with multiple autoimmune symptoms.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
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June 2010 in “Journal of acupuncture and meridian studies” A plant extract was found to effectively block an enzyme related to male hormone-related diseases.
September 2021 in “Assay and drug development technologies” Drug repurposing shows promise for treating many medical conditions.
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February 2013 in “Neuroscience Letters” Allopregnanolone may help prevent nicotine withdrawal symptoms.
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March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
January 2010 in “Acta Universitatis Medicinalis Nanjing” Progesterone helps adult male mice's brain cells survive and improves learning and memory.
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December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
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September 2010 in “Stress” Neurosteroids help protect fetal brains from asphyxia damage.
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January 1999 in “Journal of Liquid Chromatography & Related Technologies” Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
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October 2015 in “The Journal of Physiology” Combining progesterone with caffeine worsens breathing issues in newborns.
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March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.