research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
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research Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata
Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
research Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review
Quercetin may help with PCOS symptoms, but more research is needed.
research Diet in dermatology: Revisited
Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.
research Studying the genetic predisposing factors in the pathogenesis of acne vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Basics of androgen synthesis and action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research Chapter 7 Reproductive Dysfunction in Women with Epilepsy
Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
research Molecular characterization of xerosis cutis: A systematic review
It's unclear which molecules best characterize dry skin due to inconsistent findings.
research The Efficacy of 24-Month Metformin for Improving Menses, Hormones, and Metabolic Profiles in Polycystic Ovary Syndrome
Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.
research Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications
Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Acne in women
Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
research Psychological aspects of hyperandrogenic states in late adolescent and young women
Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.
research Genome-wide meta-analysis identifies novel loci conferring risk of acne vulgaris
New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.
research Genetic Variants Associated with Hyperandrogenemia in PCOS Pathophysiology
Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
research Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria
Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.
research Women's midlife health Reframing menopause
The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
research Microneedles mediated bioinspired lipid nanocarriers for targeted treatment of alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Managing Polycystic Ovary Syndrome: A Cognitive Behavioral Strategy
Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
research Revisiting hyper- and hypo-androgenism by tandem mass spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Clinical, hormonal and metabolic parameters in women with PCOS with different combined oral contraceptives (containing chlormadinone acetate versus drospirenone)
Both types of oral contraceptives improved symptoms and hormone levels in women with PCOS.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Atypical Cushing's Syndrome in Dogs: Arguments For and Against
The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.
research Dehydroepiandrosterone for women in the peri- or postmenopausal phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy
The research suggests that autophagy-related genes might play a role in causing alopecia areata.
research The role of diet in the management of psoriasis: a scoping review
Higher fiber intake may reduce psoriasis severity, but more research is needed for effective dietary strategies.