research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
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research Cutaneous xanthomas with concurrent demodicosis and dermatophytosis in a cat
A cat with skin bumps and itching had high blood fats and skin infections, which improved with diet and medication changes.
research Male Androgenetic Alopecia and Cardiovascular Risk Factors: A Case-Control Study
Balding men have higher heart disease risk.
research Niosomal delivery of pumpkin seed oil: development, characterisation, and physical stability
The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.
research Skin disease related to metabolic syndrome in women
Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.
research Need for liver evaluation in polycystic ovary syndrome
Women with PCOS often have liver disease, so liver health checks are important for them.
research Metabolic syndrome and dermatological diseases: association and treatment
Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.
research Treatment of scleromyxoedema with hydroxychloroquine
Hydroxychloroquine helped improve scleromyxoedema in patients, but caused side effects in some.
research Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research Indirect clinical markers for the detection of anabolic steroid abuse beyond the conventional doping control in athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Women’s Health Considerations for Lipid Management
The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.
research Efectos adversos de finasteride: mitos y realidades. Una revisión actualizada
Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.
research Characteristics of Malassezia furfur at various pH and effects of Malassezia lipids on skin cells
Malassezia furfur lipids improve skin health at pH 6.
research Investigating metabolic syndrome markers and body mass index changes in patients with acne vulgaris treated with isotretinoin: A prospective study
Isotretinoin effectively treats acne with low risk if dosed correctly.
research Rodent models in placental research. Implications for fetal origins of adult disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Retinoids Putting the “A” in Alopecia
Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research PREVALENCE AND PREDICTORS OF METABOLIC SYNDROME IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME- A STUDY FROM SOUTHERN INDIA
More than half of the women with PCOS in Southern India had Metabolic Syndrome, with large waist circumference being the most common feature.
research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation
CCCA involves immune response and metabolism issues, suggesting new treatment options.
research New fluorogenic probes for neutral and alkaline ceramidases
New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
research Cardiovascular risk markers and thyroid status in young Indian women with polycystic ovarian syndrome: A case-control study
Young Indian women with PCOS have a higher risk of heart disease, not linked to thyroid function but to higher levels of certain fats and homocysteine.
research Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles
Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
research Effects of non-contingent cocaine on 3alpha-androstanediol. I. Disruption of male sexual behavior
Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
research Hair cortisol in polycystic ovary syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research 4-O-Methylhonokiol: A lesser-known neolignan from Magnolia species with diverse and promising pharmacological properties
4-O-Methylhonokiol from Magnolia shows promise for hair growth, cancer, diabetes, and more, but needs better absorption.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.