46 citations
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February 2016 in “Experimental Dermatology” Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
43 citations
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October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
43 citations
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August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
41 citations
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December 2019 in “Stem Cell Reviews and Reports” Tooth regeneration could become possible by controlling how and when bioactive factors are released.
37 citations
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October 2015 in “European Journal of Human Genetics” Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.
32 citations
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June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
31 citations
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
30 citations
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April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
29 citations
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April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
27 citations
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June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
27 citations
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August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
26 citations
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September 2018 in “Journal of Molecular Cell Biology” Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
25 citations
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June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
24 citations
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April 2020 in “Cells” DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.
23 citations
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December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
19 citations
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
16 citations
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March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
15 citations
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February 2021 in “Scientific Reports” A specific group of stem cells can help regenerate hair continuously.
15 citations
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February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
14 citations
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March 2020 in “Cold Spring Harbor Perspectives in Biology” Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
13 citations
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December 2020 in “PLoS ONE” Genetic factors influence growth and brain development in children.
13 citations
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February 2020 in “Cold Spring Harbor Perspectives in Biology” New methods have helped find cells that create other cells in the body.
11 citations
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April 2017 in “Journal of The European Academy of Dermatology and Venereology” Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
10 citations
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March 2015 in “American journal of primatology” Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.
10 citations
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February 2008 in “Photochemistry and photobiology” Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.
9 citations
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January 2015 in “Fundamental & clinical pharmacology” Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
8 citations
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October 2019 in “Immunological investigations” The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.
7 citations
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March 2021 in “Biology” Scaffold improves hair growth potential.
7 citations
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March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.