research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
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research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research TGF-β family signaling in stem cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Oncogenic senescence: a multi-functional perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
research Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro
The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
research Analysis of gene expression patterns and levels in maize hybrids and their parents
Maize hybrids show better early growth due to complex gene interactions from their parent strains.
research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Revisiting the significance of keratin expression in complex epithelia
Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research All sites but skin cancer incidences analyzed worldwide by sex, age, and skin type over time (1955-2007), advancing age, and UVB dose reveals important carcinogenic drivers
Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
research Cutaneous signals of immune system disease
Skin issues can indicate immune system problems.
research Modulating the stem cell niche for tissue regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Hair follicle differentiation and regulation.
Hair follicle growth and development are controlled by specific genes and molecular signals.
research AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity
AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate
Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
research Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice
Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.
research Hormone-induced aberrations in electromagnetic adhesion signaling as a developmental factor of androgenetic alopecia
Hormones cause hair loss by affecting cell growth and weakening cell attraction.
research Expression and roles of steroidogenic acute regulatory (StAR) protein in ‘non-classical’, extra-adrenal and extra-gonadal cells and tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear-cytoplasmic labeling
Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
research Hormones
Hormones are crucial for regulating body functions and imbalances can lead to health issues.
research 316 Specialized ribosomes in human dermal fibroblast senescence
Specialized ribosomes affect aging in human skin cells.
research In Vitro Hair Dermal Papilla Cells Induction by Fagraea berteroana, a Tree of the Marquesan Cosmetopoeia (French Polynesia)
Fagraea berteroana fruit extract may promote hair growth by affecting cell proliferation and hair growth pathways.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Fibroblast bioelectric signaling drives hair growth
Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
research Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.