April 2012 in “Journal of the American Academy of Dermatology” People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
52 citations
,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
39 citations
,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” Plant-based ingredients are effective and safe for modern skincare products.
26 citations
,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
4 citations
,
October 2025 in “International Journal of Medical Sciences” Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
February 2021 in “Journal of nursing education and practice” Women and men experience different quality of life and symptom distress after kidney transplant with immunosuppressive therapy.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
254 citations
,
September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
248 citations
,
December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
151 citations
,
November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
126 citations
,
October 1983 in “Journal of The American Academy of Dermatology” Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
58 citations
,
July 2007 in “Clinics in Dermatology” Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.
53 citations
,
November 1992 in “Mayo Clinic Proceedings” HIV can cause unusual and severe skin problems that are hard to treat.
47 citations
,
August 2005 in “Facial Plastic Surgery Clinics of North America” Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
44 citations
,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
43 citations
,
May 1978 in “JAMA” Minoxidil controls blood pressure but may cause kidney damage and needs diuretics to prevent swelling.
40 citations
,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
39 citations
,
January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
38 citations
,
April 2017 in “Journal of The American Academy of Dermatology” Many skin patients have mental health issues, but few dermatologists are well-versed in treating these conditions.
38 citations
,
January 2014 in “International Journal of Endocrinology” Adrenal disorders can cause lasting brain and behavior issues in children.
37 citations
,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
30 citations
,
October 2015 in “Journal of Ethnopharmacology” Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
29 citations
,
November 2012 in “Journal of The European Academy of Dermatology and Venereology” Use 5% minoxidil or oral finasteride for mild-to-moderate hair loss, combine with hair transplant for severe cases.
29 citations
,
July 2008 in “Journal of Cutaneous Pathology” Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
29 citations
,
May 1998 in “Bulletin of the American College of Nurse-Midwifery” The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.