15 citations
,
January 2014 in “Hair therapy & transplantation” Platelet-Rich Plasma treatment has limited and temporary effects on severe Alopecia Areata and does not prevent relapses.
September 2023 in “Journal of the American Academy of Dermatology” Severe alopecia areata may increase the risk of hidden artery disease.
26 citations
,
June 1988 in “PubMed” 3% topical minoxidil is ineffective for severe chronic alopecia areata.
1 citations
,
January 2014 in “Hair therapy & transplantation” Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.
2 citations
,
January 2025 in “Allergy” Having asthma, atopic dermatitis, or Hashimoto's thyroiditis increases the risk of severe and long-lasting alopecia areata.
April 2023 in “Journal of Investigative Dermatology” IL-17 plays a key role in severe hair loss in chronic alopecia areata.
September 2019 in “Journal of Investigative Dermatology” IL-17 and certain immune cells are linked to more severe alopecia areata.
3 citations
,
January 2023 in “JEADV Clinical Practice” IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.
18 citations
,
January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
September 2025 in “Australasian Journal of Dermatology” New medications could improve treatment for severe alopecia areata in Australia.
October 2025 in “International Journal of Risk & Safety in Medicine” Oral tofacitinib successfully treated a girl's severe skin and hair conditions.
3 citations
,
March 2020 in “International Journal of Dermatology” Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.
3 citations
,
July 2025 in “Clinical and Experimental Dermatology” Ritlecitinib may be more effective for severe alopecia areata than conventional treatments.
August 2024 in “British Journal of Dermatology” Rezpegaldesleukin shows promise for treating severe alopecia areata.
June 2023 in “British Journal of Dermatology” Baricitinib was effective and safe for severe hair loss treatment over 6 months.
High CCL11 levels may indicate poor response to baricitinib in severe alopecia areata.
6 citations
,
July 2022 in “Journal of health economics and outcomes research” Adolescents with severe alopecia incur significantly higher healthcare costs.
2 citations
,
June 2018 in “Clinical and Experimental Dermatology” Permanent hair loss after a stem cell transplant can be a sign of chronic immune system attack on the scalp.
42 citations
,
June 2012 in “Clinical and Experimental Dermatology” Black dots under trichoscopy can appear in different hair and scalp conditions, not just in alopecia areata.
1 citations
,
January 2015 in “Springer eBooks” The document says a skin condition called alopecia areata causes hair loss and stress, and is treated with strong skin creams, injections, or other therapies, but treatment success varies.
1 citations
,
April 2016 in “Journal of The American Academy of Dermatology” People with allergies or high eosinophil levels have a higher chance of severe hair loss from alopecia areata, and sudden hair loss can indicate chronic graft-versus-host disease.
3 citations
,
January 2011 in “International journal of trichology” Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.
19 citations
,
September 2004 in “PubMed” Chronic hair diseases can severely affect mental health and self-confidence.
Chronic hair diseases can severely impact mental health and self-confidence.
1 citations
,
September 2025 in “JAAD reviews.” Janus kinase inhibitors are effective for severe alopecia areata, promoting hair regrowth.
July 2025 in “Clinical Dermatology Review” Azathioprine can cause unexpected hair loss and severe bone marrow issues, so careful monitoring is needed.
24 citations
,
January 2017 in “Pediatric dermatology” 1% anthralin ointment is effective and safe for treating severe alopecia areata in children.
2 citations
,
September 2022 in “Dermatologic Therapy” Tofacitinib is a promising treatment for severe alopecia areata, with many patients experiencing complete or partial hair regrowth.
11 citations
,
January 2022 in “Journal der Deutschen Dermatologischen Gesellschaft” Alopecia areata is a chronic condition causing hair loss, with new treatments targeting the immune system showing promise.
24 citations
,
June 2016 in “Acta dermato-venereologica” Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.