September 2009 in “Hair transplant forum international” A committee was formed to improve hair restoration for certain hair diseases by collecting and analyzing data.
June 2007 in “Journal of Investigative Dermatology” Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
44 citations
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November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
42 citations
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January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
30 citations
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November 2013 in “Journal of The American Academy of Dermatology” Elastin staining helps assess late-stage scarring alopecia but is not definitive, and clinical diagnosis is still crucial.
20 citations
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July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
15 citations
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February 2003 in “British Journal of Dermatology” The study suggests computer-assisted analysis of scalp biopsies could improve hair loss diagnosis but needs more validation.
14 citations
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October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
12 citations
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January 2016 in “Skin appendage disorders” Hair restoration surgery can potentially treat primary scarring alopecias, but it's important to start early medication, ensure patient remission before transplant, and monitor after surgery.
12 citations
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June 2015 in “Dermatology Reports” Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.
2 citations
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January 2021 in “Przegląd Dermatologiczny (1959)” The article discusses various treatments for different types of non-scarring hair loss.
January 2026 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Primary cicatricial alopecia causes permanent hair loss by destroying hair follicles, and its exact cause is unknown.
December 2025 in “Russian Journal of Skin and Venereal Diseases” Hair follicles are thinner in alopecia patients, especially in alopecia areata.
November 2025 in “International Journal of Research in Medical Sciences” Diffuse alopecia in females is often linked to certain medications, diseases, and low hemoglobin, while female pattern hair loss is linked to age, duration, and family history.
March 2024 in “Journal of Investigative Dermatology” People with Primary Cicatricial Alopecia have a higher risk of heart disease.
September 2023 in “Medicina-lithuania” The study suggests that analyzing DNA can help treat hair loss, but more research is needed.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
August 2021 in “Al-Azhar International Medical Journal (Print)” Hair transplantation is effective for treating cicatricial alopecia with fewer anesthesia risks, scars, and recovery time.
March 2021 in “CRC Press eBooks” The document concludes that different patterns of hair thickness and scalp changes can help diagnose types of non-scarring hair loss.
January 2020 in “JAAD case reports” Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
October 2018 in “Biomedical Journal of Scientific & Technical Research” Otoplasty can cause permanent hair loss if bandages are too tight.
March 2015 in “Zagazig University Medical Journal” Damage to hair follicle stem cells may cause permanent hair loss and scarring in PCA.
December 2013 in “Research Portal (King's College London)” Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
December 2012 in “Drugs & Therapy Perspectives” Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.
Accurate diagnosis of cicatricial alopecias requires thorough scalp examination and multiple biopsy techniques.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
New treatments for hair loss show promise, especially with antiandrogens, minoxidil, and autoimmune therapies.
November 2022 in “Frontiers in Medicine” PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.
December 2020 in “Journal of Endocrinology and Reproduction” Certain inflammatory molecules and leptin may contribute to hair loss in cicatricial alopecia.
September 2018 in “Journal of the American Academy of Dermatology” Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.