135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
129 citations
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October 2017 in “BMC Genomics” The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.
129 citations
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May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
124 citations
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February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
112 citations
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February 2001 in “Journal of Investigative Dermatology” Neuropeptides affect hair growth, with some speeding it up and others slowing it down.
111 citations
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June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
107 citations
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October 2014 in “PeerJ” Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
106 citations
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February 2014 in “eLife” Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
103 citations
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March 2015 in “Nature Communications” A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
103 citations
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June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
97 citations
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January 2014 in “Journal of The American Academy of Dermatology” Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
91 citations
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March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
83 citations
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October 1998 in “The American Journal of Human Genetics” A specific gene mutation causes complete hair loss in an Irish Traveller family.
75 citations
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September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
67 citations
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June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
67 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.
66 citations
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January 2000 in “Dermatology” Dandruff is a common, winter-worsened scalp condition linked to inflammation and microorganisms, treatable with products like ketoconazole, and may affect hair loss.
64 citations
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January 2009 in “The International journal of developmental biology” Hair follicle stem cells are controlled by their surrounding environment.
62 citations
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March 2011 in “European journal of endocrinology” Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
59 citations
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January 2021 in “Genes” Twelve key genes may improve cashmere production by influencing hair follicle cycles.
54 citations
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May 2018 in “Journal of The European Academy of Dermatology and Venereology” Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.
52 citations
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February 2018 in “Diabetology & Metabolic Syndrome” Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.
46 citations
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May 2020 in “Cureus” Zinc is vital for immune health, growth, and preventing diarrhea.
43 citations
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July 2013 in “Pharmacological reviews” New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.
41 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.
40 citations
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March 2018 in “Aesthetic Surgery Journal” New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.
39 citations
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May 2011 in “European Journal of Clinical Investigation” Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.
38 citations
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July 2020 in “EMBO journal” SIRT7 protein is crucial for starting hair growth in mice.
36 citations
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June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.