research Convergent Decay of Skin-specific Gene Modules in Pangolins
Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.
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570-600 / 1000+ results research Development and Maintenance of Epidermal Stem Cells in Skin Adnexa
Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.
research Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12
The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.
research Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata
CD44 variant changes start alopecia areata, but don't maintain it.
research Characterization of surface deposits on human hair fibers
research Review: Evolution and diversification of corneous beta‐proteins, the characteristic epidermal proteins of reptiles and birds
Corneous beta-proteins evolved uniquely in reptiles and birds, forming scales, claws, beaks, and feathers.
research EDA Missense Variant in a Cat with X-Linked Hypohidrotic Ectodermal Dysplasia
A genetic mutation in the EDA gene causes hypohidrotic ectodermal dysplasia in cats.
research Disruption of P2RY5, an orphan G protein–coupled receptor, underlies autosomal recessive woolly hair
Mutations in the P2RY5 gene cause autosomal recessive woolly hair.
research The variable cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research Commentary on: Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
The commentary explains that a balance of HR protein and putrescine is important for normal hair growth.
research Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
Overexpression of ΔNLef1 in mouse skin leads to hair loss, cysts, and skin tumors.
research Hair structure anatomy and comparative anatomy1 1Dedicated to the memory of the late Dr. R. E. Rivett whose untimely death prevented his role in co-authorship.
Human hair is complex and grows in cycles starting from embryonic life.
research Expression ofSfrp2Is Increased in Catagen of Hair Follicles and Inhibits Keratinocyte Proliferation
Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research iRhom2 Mutation Leads to Aberrant Hair Follicle Differentiation in Mice
A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
research Development, Structure, and Keratin Expression in C57BL/6J Mouse Eccrine Glands
The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
research Atrichia with papular lesions
Accurate diagnosis of APL is crucial to avoid unnecessary treatments.
research Dermoscopic Approach to a Small Round to Oval Hairless Patch on the Scalp
Dermoscopic examination helps diagnose different types of hair loss conditions by showing specific patterns.
research A Case of Loose Anagen Hair Syndrome in a Southeast Asian Boy
A Thai boy was diagnosed with a rare hair disorder causing hair thinning and shedding.
research Exploring Mechanical Niches Identified by Hair Follicle Compression and How These Transduce Proliferation and Differentiation Cues in Epidermally Derived cells.
Less stiff collagen promotes higher cell growth in hair follicles.
research Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle
The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
research Histopathological Analysis on keratin2-6 g Expression in Hair Mutant Mouse Hague
Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.
research The accelerated aging skin in rhino‐like SHJHhr mice
The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
research Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice
A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.
research Pathologic Hairpulling, Skin Picking, and Nail Biting
Hairpulling, skin picking, and nail biting cause significant harm and need more research for better treatments.
research Beauty is skin deep: the fascinating biology of the epidermis and its appendages.
The biology of skin and hair is complex and not fully understood.
research Metamorph analysis and quantification of activated eccrine glands in alopecia areata
Eccrine gland activity may be linked to alopecia areata.
research Insights on the mechanical behavior of keratin fibrils
Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
research INFLUENCE OF CLIPPING AND CHEMICAL EPILATION ON HAIR GROWTH IN MICE1
Certain treatments can speed up local hair growth in mice but don't change the overall hair growth pattern.