January 2011 in “Guangdong Medical Journal” Low Vitamin D receptor levels in hair follicles may contribute to alopecia areata.
April 2023 in “Journal of Investigative Dermatology” The research found that certain factors in hair follicle cells control hair growth and development, and these could be used to create new treatments for hair loss.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
4 citations
,
November 2020 in “BMC Dermatology” Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
Higher PD-1 levels mean fewer CD8+ T cells in alopecia areata hair follicles.
26 citations
,
January 2018 in “Skin appendage disorders” Thallium, mercury, selenium, and colchicine strongly cause hair loss.
105 citations
,
April 2005 in “Cell” Hair graying happens because certain cells aren't maintained properly.
1 citations
,
September 2020 in “Journal of Dermatological Science” The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” MEF2C is crucial for normal hair cycle progression.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
3 citations
,
May 2008 in “Hair transplant forum international” Common hair loss disorders may not need stem cell therapy, but could benefit from other treatments like hair cycle control and immune restoration therapy.
175 citations
,
August 1997 in “Nature Genetics”
June 2022 in “Journal of Dermatology Research” Using 448-kHz Capacitive-Resistive Electrothermal Therapy can help increase hair density and prevent hair loss in women.
223 citations
,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
A 5-year-old girl has sparse, dry, and brittle hair but is otherwise healthy.
54 citations
,
December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
3 citations
,
January 2021 in “Wear” Hair's resistance to wear varies by ethnicity and treatment, with less wear indicating stronger hair.
March 2009 in “Medical & surgical dermatology” Women with androgenetic alopecia have fewer terminal hairs, phenol in nail surgery is safe, and a new hair transplant method is faster and less damaging.
March 2006 in “Chinese journal of plastic surgery” Microencapsulated human hair cells can regenerate hair follicles in mice ears.
13 citations
,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
16 citations
,
October 2012 in “British Journal of Dermatology” Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
November 2025 in “Journal of Investigative Dermatology” Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.
April 2023 in “Journal of Investigative Dermatology” A new image-based method improves accuracy in measuring hair loss in mice.
3 citations
,
September 2014 in “SpringerPlus” Human hair loss may have evolved to help increase brain size.
April 2017 in “Journal of Investigative Dermatology” Dermal Wnt/β-catenin signaling is important for the proper size and development of hair follicles.
August 2016 in “Journal of Investigative Dermatology” Human hair follicles have a scent receptor that can influence hair growth.
17 citations
,
January 2010 in “International journal of trichology” A man experienced hair loss from radiotherapy, which can be temporary or permanent depending on radiation dose, with potential treatments available.