K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
47 citations
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July 1997 in “British Journal of Dermatology” The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
August 2024 in “Archives of Dermatological Research” CHI3L1 and CXCL5 proteins help promote hair growth.
272 citations
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September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
November 2022 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by affecting hair follicles.
12 citations
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January 2013 in “Acta Histochemica” Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.
5 citations
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October 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
24 citations
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November 2015 in “Scientific reports” Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
March 2009 in “Chinese Journal of Dermatology” Melanocytes in the outer root sheath are likely stem cells that grow fast but stay immature.
January 2002 in “Basic medical sciences and clinics” Hair follicle stem cells are crucial for hair growth and renewal.
205 citations
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April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
4 citations
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July 2010 in “International Journal of Cosmetic Science” Curved human hair has different structures on its convex and concave sides.
65 citations
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May 2006 in “Journal of Structural Biology” Hair curliness is due to uneven distribution of different cortices within the hair fiber.
12 citations
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July 2019 in “Veterinary Dermatology” Nestin-expressing progenitor cells become outer root sheath keratinocytes.
17 citations
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September 2014 in “PLoS ONE” SK2 channels help control sensory signals in rat muscle spindles and hair follicles.
29 citations
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April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
27 citations
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January 2006 in “Colloids and Surfaces B: Biointerfaces” Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
September 2016 in “Journal of Dermatological Science” Hair follicle stem cells can become heart muscle cells.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
135 citations
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November 1987 in “Differentiation” Outer root sheath cells consistently express certain keratins influenced by their environment.
9 citations
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April 2019 in “Journal of structural biology” Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.
9 citations
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July 2014 in “PubMed” Different S100 proteins have specific roles in various parts of the hair follicle.
1 citations
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January 2007 in “AIP conference proceedings” High-resolution x-ray images showed three main structures in human hair: medulla, cortex, and cuticle.
130 citations
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January 1994 in “Differentiation” Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
32 citations
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February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
4 citations
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April 2019 in “Cosmetics” Hair stiffness is higher when it has more para-like cortical cells.
109 citations
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April 1997 in “Archives of Dermatological Research” Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
173 citations
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July 1995 in “Biochemical and biophysical research communications” Male hormones promote hair cell growth by using a growth factor from nearby skin cells.
90 citations
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.