research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
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90-120 / 1000+ results research Folate Supplementation and Age-Related Hearing Loss
Folic acid might help with age-related hearing loss.
research Molecular basis of hair cell loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research Ototoxicity of Common Topical Antimycotic Preparations
Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
research Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research PŁYNY- NIE ZA DUŻO, NIE ZA MAŁO, LECZ W SAM RAZ
AI and new therapies show promise in medicine, especially for cancer and regenerative treatments.
research Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Cancer vaccine strategies and studies of human thioredoxin reductase splice variants
Vaccines and targeting TrxR variants can help prevent cancer and reduce metastasis.
research Activity evaluation of epidermo-melanin unit and dermal damage in melasma
Melasma results from changes in the skin's pigment and structure, not just pigment cell growth.
research Melanocytes: The new Black
Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
research Regulation of melanocyte stem cell behavior by the niche microenvironment
The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
research Somatic mutations distinguish melanocyte subpopulations in human skin
Hair follicles protect melanocytes from sun damage, helping them replenish skin.
research Melanocytes: A possible autoimmune target in alopecia areata
Melanocytes might be targeted by the immune system in people with alopecia areata, but more research is needed.
research Mode of redifferentiation and melanogenesis of melanocytes in mouse hair follicles
research The distribution of melanocytes and the degradation of melanosomes in fetal hair follicles
Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.
research Changes in Different Melanocyte Populations During Hair Follicle Involution (Catagen)
Different melanocyte types in hair follicles either survive or die during the catagen phase.
research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Photo‐protective effect of cuttlefish ink melanin on human hair
Cuttlefish ink melanin protects hair from UV damage.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Clinical Snippets
Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.
research Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research Photochemical alterations in human hair. I. Artificial irradiation and investigations of hair proteins
Melanin in black hair protects it from sun damage better than light-brown hair.
research Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes
Hair follicle stem cells can become melanocytes to help treat skin depigmentation.
research Histopathologic Findings of Cutaneous Hyperpigmentation in Addison Disease and Immunostain of the Melanocytic Population
The study found increased skin pigmentation and variable melanocyte density in a patient with Addison's disease.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research 576 A preliminary study of melanogenic markers in the differentiation of the human hair follicle melanin unit
The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
research Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata
Lower MC2R expression may contribute to alopecia areata.
research Splenic melanosis during normal murine C57BL/6 hair cycle and after chemotherapy.
Chemotherapy reduces splenic melanin in mice.
research Preservation of melanoblasts of white hair follicles of segmental vitiligo lesions: A preliminary study
White hair follicles in vitiligo have fewer and less functional melanocytes.
research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.