research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
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60-90 / 1000+ results research Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride
The research helps understand how finasteride works and aids drug development.
![Synthesis and Structural Characterization of a New Dinuclear Platinum(III) Complex, [Pt2Cl4(NH3)2{μ-HN=C(O)Bu^t}2]](/images/research/fcbeee85-f5bd-406e-936d-9134a0f200d4/small/36266.jpg)
research Synthesis and structural characterization of a new dinuclear platinum(III) complex, [Pt2Cl4(NH3)2{μ-HN=C(O)But}2]
A new platinum complex was made and studied, which might help fight cancer better.
research Author response: Structural basis of malodour precursor transport in the human axilla
The transporter protein SH1446 in Staphylococcus hominis is key to underarm odor production.
research 17α-Acetoxy-6-bromo-16β-methylpregna-4,6-diene-3,20-dione
A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.
research Decision letter: Structural basis of malodour precursor transport in the human axilla
The study identified a key protein involved in producing underarm odor and found ways to inhibit it.
research Structures of three polycystic kidney disease-like domains fromClostridium histolyticumcollagenases ColG and ColH
The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research An overview on 5α-reductase inhibitors
5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
research Crystallization of organic compounds : an industrial perspective
Understanding and controlling crystallization is crucial for producing high-quality organic compounds in industry.
research Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex
Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
research SYNTHESIS OF SILICA NANOPARTICLES VIA GREEN APPROACH BY USING HOT AQUEOUS EXTRACT OF THUJA ORIENTALIS LEAF AND THEIR EFFECT ON BIOFILM FORMATION
Silica nanoparticles made with cold plasma method best stop bacteria growth.
research Ultramicroscopic study on the hair of newly found 15th century mummy in Daejeon, Korea
The 15th-century Korean mummy's hair was well-preserved due to a protective lime-soil coating.
research The Binding of Small Molecules and Polymers to Keratin and Their Effects on the Physicochemical and Surface Properties of Hair Fibers
Certain small molecules and polymers can change hair's physical properties and how it feels by affecting the bonds within the hair.
research The mineralization of hair follicle tissue
Hair follicle tissue can induce mineral formation, likely due to a potent nucleator.
research Evaluating The Cytotoxic Effects Of Silver Nanoparticles Derived From Pogostemon Benghalensis Brum. F. Kunth. Extract On A549 Lung Cancer Cells
Silver nanoparticles from Pogostemon benghalensis may effectively fight lung cancer cells.
research Hair today, toothpaste tomorrow
Keratin could help create enamel-regenerating toothpaste in a few years.
research Gouty Alopecia: An Intriguing Manifestation of Disseminated Tophaceous Gout
Gout can cause hair loss, but treatment can lead to hair regrowth.
research The Effect of Green Synthesis ZnO NPs on Sun Protection Factor of Sunblock Lotion
Adding more zinc oxide nanoparticles increases sunblock SPF.
research Hydrocolloid Use in the Treatment of Thermal Injury in a Dog
Hydrocolloid dressings significantly improved healing of a dog's third-degree burn.
research Understanding the Effect on Hair Fibers of Coloring and Bleaching Formulations Using High Pressure Differential Scanning Calorimetry (HPDSC)
Hair coloring and bleaching can permanently break down hair protein and temporarily change its properties.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors
New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.
research Penetration of drugs through skin, a complex rate-controlling membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Nanocrystals of medium soluble actives—Novel concept for improved dermal delivery and production strategy
Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
research Distribution and Localization of Hydrophobic and Ionic Chemical Groups at the Surface of Bleached Human Hair Fibers
Bleaching hair removes its protective top layer and exposes more hydrophilic groups, changing its chemical surface and affecting how it interacts with products.
research In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss
Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.
research Further errors in polymorph identification: furosemide and finasteride
Errors found in identifying furosemide and finasteride polymorphs due to incomplete data.
research Investigation of intermolecular interactions in finasteride drug crystals in view of X-ray and Hirshfeld surface analysis
Finasteride crystals are held together by hydrogen bonds and weak interactions, forming synthon pseudopolymorphs.