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research A randomized pilot study to compare hair follicle cell suspensions prepared using trypsin alone versus trypsin in combination with collagenase type I for transplantation in vitiligo

5 citations , July 2019 in “Clinical and experimental dermatology”

Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.

research Localization of Type I Human Skin Collagenase in Developing Embryonic and Fetal Skin

22 citations , June 1994 in “Journal of Investigative Dermatology”

research Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles

30 citations , February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Plet-1 protein helps hair follicle cells move and stick to tissues.

research Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination

56 citations , December 1990 in “Differentiation”

Growth factors can either promote or inhibit hair follicle cell growth and collagen breakdown.

research Expression of extracellular matrix in hair follicle mesenchyme in alopecia areata

11 citations , December 1990 in “British Journal of Dermatology”

Alopecia areata may involve disrupted mesenchymal function in hair follicles.

research Distribution of Type XII and XIV Collagens in Bovine Dermis and Hair Follicles

September 2001 in “Connective tissue”

Type XII and XIV collagens help maintain hair follicle structure in bovine skin.

research Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression.

26 citations , January 2015 in “PubMed”

Collagenase IV helps control hair growth by affecting certain growth factors.

research Correlation of proteolytic activities of organ cultured intact mouse skin with defined hair cycle stages

28 citations , June 1994 in “Journal of Dermatological Science”

Proteolytic activity in mouse skin changes with hair cycle stages, peaking in early anagen.

research Eco-engineered recombinant collagen III-PEG hydrogels with curcumin synergy for accelerated skin regeneration: A green crosslinking strategy in wound therapeutics

September 2025 in “International Journal of Biological Macromolecules”

The new hydrogel with curcumin speeds up wound healing safely and effectively.

research Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation

56 citations , November 2003 in “Journal of Investigative Dermatology”

MMP-19 may worsen skin diseases by affecting skin growth and inflammation.

research Screening and culture of human vaginal mucosa stem cells

January 2008 in “Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu”

Vaginal mucosa stem cells can be effectively isolated and cultured using specific methods.

research Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling

15 citations , August 2020 in “American Journal of Pathology”

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.

research LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

53 citations , June 1993 in “Proceedings of the National Academy of Sciences of the United States of America”

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition

174 citations , November 2016 in “Cell stem cell”

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

research Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp

4 citations , September 2012 in “Journal of dermatological science”

The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.

research Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis

12 citations , February 1997 in “British Journal of Dermatology”

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

research The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages

36 citations , January 2007 in “Archives of Histology and Cytology”

Type IV collagen chains vary in different parts of human skin, with specific patterns linked to melanocytes.

research Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells

17 citations , April 2007 in “Kidney international”

Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.

research 115 Distributions of type XII and XIV collagens in adult skin and the anagen hair follicle

July 1995 in “Journal of Dermatological Science”

Effects of Polygoni Multiflori Radix on Elastase and Collagenase Activities and Procollagen Synthesis in Hs68 Human Fibroblasts

research Effects of Polygoni Multiflori Radix on the Elastase, and Collagenase Activities and the Procollagen Synthesis in Hs68 Human Fibroblasts

2 citations , January 2014 in “The Korea Journal of Herbology”

Polygoni Multiflori Radix may help reduce skin aging by lowering collagenase and elastase activity.

research Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression

27 citations , September 2015 in “Drug Design Development and Therapy”

Collagenase IV is crucial for hair growth by affecting key growth factors.

Structures of Three Polycystic Kidney Disease-Like Domains from Clostridium Histolyticum Collagenases ColG and ColH

research Structures of three polycystic kidney disease-like domains fromClostridium histolyticumi>collagenases ColG and ColH

18 citations , February 2015 in “Acta Crystallographica Section D: Structural Biology”

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

research Melanocytes from the Outer Root Sheath of Hair Follicles Cultivated on Collagen Membrane Improve their Melanotic Properties
5 citations , January 2012 in “Journal of Tissue Science & Engineering”

Collagen membranes improve melanocyte growth for treating skin depigmentation.

research Type XVII collagen coordinates proliferation in the interfollicular epidermis
124 citations , July 2017 in “eLife”

Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.

research Biological Macromolecule Hydrogel Based on Recombinant Type I Collagen/Chitosan Scaffold to Accelerate Full-Thickness Healing of Skin Wounds
12 citations , September 2023 in “Polymers”

The hydrogel speeds up skin wound healing effectively.

research TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells
September 2023 in “Research Square (Research Square)”

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

research Unravelling the link between insulin resistance and androgen excess
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)”

AKR1C3 could be a treatment target for metabolic issues in PCOS.

research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
7 citations , October 2024 in “Frontiers in Immunology”

A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.

research Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study
April 2024 in “Lasers in medical science”

Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.

research Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice
29 citations , March 2020 in “Stem Cell Research & Therapy”

Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.

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