research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
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research Therapeutic Approach to Androgenetic Alopecia
Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research A systematic review of commonly used medical treatments for hirsutism in women
Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
research A comparative study of Aldactone® and Diane® in the treatment of hirsutism
Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
research Efficacy and safety of systemic spironolactone for acne in female patients in Sulaymaniyah teaching center of dermatology
Spironolactone is effective and safe for treating acne in women, especially those over 25 with hormonal imbalances.
research A novel topical combination of minoxidil and spironolactone for androgenetic alopecia: Clinical, histopathological, and physicochemical study
Minoxidil and spironolactone combo effectively treats androgenetic alopecia, improving hair density and diameter.
research Male sex hormones, aging, and inflammation
Adequate testosterone is crucial for men's health and quality of life, but its decline with age needs more research.
research A Case of Gynecomastia Induced by Use of Doxazosin
Doxazosin can cause male breast growth and milk production.
research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research HAIR REGROWTH
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Hair: What is New in Diagnosis and Management?
Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Clinical use of 5α-reductase inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Treatment of hirsutism with the pure antiandrogen flutamide
Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
research Management of Hirsutism
Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Steroidogenesis in steroid related cancers
Steroid-producing capabilities in certain cancers may contribute to treatment resistance.
research The role of dutasteride in the treatment of benign prostatic obstruction and related conditions
Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.
research Mechanistic synergy of hair growth promotion by the Avicennia marina extract and its active constituent (avicequinone C) in dermal papilla cells isolated from androgenic alopecia patients
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
research Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia
Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research An Asian traditional herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta and green tea stimulates hair growth in mice
The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.
research A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
research Progestogens in menopausal hormone therapy
Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.
research Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review
Oral spironolactone's effectiveness for adult female acne is not well-supported by strong evidence.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.