research Transcriptomic profiling in Silurana tropicalis testes exposed to finasteride
Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
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research Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment
The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
research ACNE
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
research The Role of Oral Contraceptives in the Treatment of Hyperandrogenic Disorders
Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
research Hormonal prevention of prostate cancer
Suppressing certain hormones might help prevent prostate cancer.
research Prostate-Sparing Effects in Primates of the Potent Androgen 7α-Methyl-19-Nortestosterone: A Potential Alternative to Testosterone for Androgen Replacement and Male Contraception1
MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
research Markers of peripheral androgen action in vivo and in vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Evaluation of the Effects of Dorema aucheri (Bilhar) Hydroalcoholic Extract on Wound Healing of Streptozotocin‐Induced Diabetic Rats: A Stereological Study
A 5% concentration of Dorema aucheri extract significantly improves diabetic wound healing.
research PENGEMBANGAN PENYUBUR RAMBUT MENGGUNAKAN KOMBINASI EKSTRAK ETANOL HERBA PEGAGAN (Centella Asiatica (L) Urban) DAN EKSTRAK N-HEKSANA BAWANG PUTIH (Allium Sativum L)
The best hair growth results were achieved with a hair tonic containing 5% gotu kola extract and 0.04% garlic extract.
research Comparative Study on Antioxidant Potential of Schinus terebinthifolius Extracts Prepared by Conventional Extraction, Accelerated Solvent Extraction, and Pulsed Electric Field Method
The conventional extraction method with 50% ethanol was the most effective for antioxidant activity.
research Substantiation of technological parameters of the oil extract obtained from Urtica dioica roots based on the yield determination of phytosterols using capillary gas chromatography method
The best way to extract oil from Urtica dioica roots is by using corn oil, a 1:5 ratio of raw material to extract, extracting for 6 hours, and using the maceration method.
research Thallium
Thallium exposure can cause serious health issues, including nerve damage and hair loss.
research Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-like Congenital Hypotrichosis
Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Biotransformation of Finasteride by Ocimum sanctum L., and tyrosinase inhibitory activity of transformed metabolites: Experimental and computational insights
Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles
Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.
research Experimental and Clinical Pharmacology ofZiziphus jujubaMills
Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.
research Toxicological Studies on Procyanidin B-2 for Extern?al Application as a Hair Growing Agent
Procyanidin B-2 is safe to use on skin as a hair growth product.
research Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome Coronavirus
Five existing drugs may help fight Swine Acute Diarrhea Syndrome Coronavirus.
research A COMPREHENSIVE REVIEW ON PHARMACOLOGICAL POTENTIALS OF CAFFEINE
Caffeine boosts alertness, helps breathing, acts as a diuretic, and may aid cancer treatment.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Development of Stable and Simple Finasteride 333-μg/mL Suspensions that Minimize Occupational Exposure.
A stable and simple finasteride suspension was developed that retains over 94.3% of its concentration for up to 90 days and doesn't significantly increase occupational exposure, but safety measures are still advised.
research Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles
Six existing drugs may help block virus entry in COVID-19.
research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research In Vitroandin VivoStructure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research A Facile Synthesis of Mollugin
Mollugin may help treat diseases and boost hair growth and anti-aging.
research Progress of ursolic acid on the regulation of macrophage: summary and prospect
Ursolic acid may help develop new anti-inflammatory drugs by affecting immune cells.
research Chromatographic Methods for the Determination of Aminexil, Pyridoxine, and Niacinamide in a Novel Cosmetic Hair Preparation
Two new methods accurately measure Aminexil, Pyridoxine, and Niacinamide in hair products.